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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TCEB3B
All Species:
7.27
Human Site:
S277
Identified Species:
14.55
UniProt:
Q8IYF1
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYF1
NP_057511.2
753
83921
S277
S
A
R
D
R
Q
P
S
D
F
K
T
D
K
E
Chimpanzee
Pan troglodytes
XP_523920
753
84039
S277
S
A
R
D
R
Q
P
S
D
F
K
T
D
K
E
Rhesus Macaque
Macaca mulatta
XP_001091087
754
84239
S277
S
A
R
D
R
P
S
S
G
D
A
K
D
K
E
Dog
Lupus familis
XP_535361
848
95731
L372
R
G
D
G
K
S
S
L
S
R
E
K
S
H
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CB77
773
87159
K297
S
S
V
V
K
K
D
K
D
R
E
G
S
S
L
Rat
Rattus norvegicus
Q63187
773
87185
E297
P
S
S
V
V
K
K
E
K
D
R
E
G
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521771
748
82742
R276
G
P
K
R
E
K
E
R
E
G
G
G
S
R
K
Chicken
Gallus gallus
NP_001026076
779
87927
R310
N
R
E
N
S
S
S
R
K
E
K
L
H
V
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998620
622
70138
P170
N
N
I
R
H
S
K
P
H
K
E
P
V
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCP0
643
71143
E191
K
E
K
K
S
N
G
E
H
K
S
K
D
S
S
Honey Bee
Apis mellifera
XP_396851
659
74896
R207
S
M
D
K
S
K
R
R
K
Y
S
D
S
E
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797640
908
98406
N294
S
S
G
S
E
K
S
N
E
R
S
L
S
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
79.1
31.9
N.A.
45.5
47.2
N.A.
35.7
38.7
N.A.
32.1
N.A.
22.5
24
N.A.
25.5
Protein Similarity:
100
96.1
83.6
47.1
N.A.
61.1
62.4
N.A.
51.3
54.5
N.A.
45.2
N.A.
39.4
42
N.A.
40
P-Site Identity:
100
100
60
0
N.A.
13.3
0
N.A.
0
6.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
60
20
N.A.
40
20
N.A.
33.3
26.6
N.A.
26.6
N.A.
13.3
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
0
0
0
0
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
25
0
0
9
0
25
17
0
9
34
0
0
% D
% Glu:
0
9
9
0
17
0
9
17
17
9
25
9
0
9
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% F
% Gly:
9
9
9
9
0
0
9
0
9
9
9
17
9
0
0
% G
% His:
0
0
0
0
9
0
0
0
17
0
0
0
9
9
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
17
17
17
42
17
9
25
17
25
25
0
34
17
% K
% Leu:
0
0
0
0
0
0
0
9
0
0
0
17
0
0
9
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
17
9
0
9
0
9
0
9
0
0
0
0
0
9
9
% N
% Pro:
9
9
0
0
0
9
17
9
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
9
% Q
% Arg:
9
9
25
17
25
0
9
25
0
25
9
0
0
17
0
% R
% Ser:
50
25
9
9
25
25
34
25
9
0
25
0
42
17
25
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% T
% Val:
0
0
9
17
9
0
0
0
0
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _