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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZZZ3 All Species: 20.61
Human Site: S472 Identified Species: 75.56
UniProt: Q8IYH5 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IYH5 NP_056349.1 903 102023 S472 H L P S A K E S A S Q H I T E
Chimpanzee Pan troglodytes XP_513508 903 101976 S472 H L P S A K E S A S Q H I T E
Rhesus Macaque Macaca mulatta XP_001103569 903 101870 S472 H L P S A K E S A S Q H I T E
Dog Lupus familis XP_547324 903 102069 S472 H L P S A K E S A N P H N T E
Cat Felis silvestris
Mouse Mus musculus Q6KAQ7 910 102288 S479 H L P S A K E S A S Q H T A E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506419 1003 111451 S572 Y L P P A K E S A N L H I A E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391891 388 44955
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.5 95.6 N.A. 86.6 N.A. N.A. 70.7 N.A. N.A. N.A. N.A. N.A. 22.5 N.A. N.A.
Protein Similarity: 100 99.8 99.3 98.2 N.A. 92.4 N.A. N.A. 78.3 N.A. N.A. N.A. N.A. N.A. 30.7 N.A. N.A.
P-Site Identity: 100 100 100 80 N.A. 86.6 N.A. N.A. 66.6 N.A. N.A. N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 N.A. N.A. 80 N.A. N.A. N.A. N.A. N.A. 0 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 86 0 0 0 86 0 0 0 0 29 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 86 0 0 0 0 0 0 0 86 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 72 0 0 0 0 0 0 0 0 0 0 86 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 58 0 0 % I
% Lys: 0 0 0 0 0 86 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 86 0 0 0 0 0 0 0 0 15 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 29 0 0 15 0 0 % N
% Pro: 0 0 86 15 0 0 0 0 0 0 15 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 58 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 72 0 0 0 86 0 58 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 15 58 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _