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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf53
All Species:
22.73
Human Site:
S245
Identified Species:
62.5
UniProt:
Q8IYJ0
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYJ0
NP_710152.1
282
30076
S245
V
L
G
A
F
G
D
S
P
T
P
T
P
D
H
Chimpanzee
Pan troglodytes
XP_508963
343
35546
S306
V
L
G
A
F
G
D
S
P
T
P
T
P
D
H
Rhesus Macaque
Macaca mulatta
XP_001107986
276
29408
S245
V
L
G
A
F
G
D
S
P
T
P
T
P
D
H
Dog
Lupus familis
XP_854420
210
22341
I199
I
V
L
V
A
T
G
I
I
F
K
F
W
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1B3
278
29725
S241
V
L
G
A
F
G
D
S
P
T
P
T
P
D
H
Rat
Rattus norvegicus
Q5U2P6
272
29114
S241
V
L
G
A
F
G
D
S
P
T
P
T
P
D
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518109
222
23445
T211
I
L
G
E
A
P
A
T
L
R
P
F
L
F
G
Chicken
Gallus gallus
XP_416507
304
33214
S265
I
L
G
P
Y
S
D
S
L
T
P
T
S
E
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074455
187
21076
L176
Q
E
D
S
R
Q
T
L
H
S
T
P
S
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.3
97.8
71.9
N.A.
92.9
91.8
N.A.
20.9
60.2
N.A.
23
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
81.9
97.8
73
N.A.
93.9
92.1
N.A.
29.4
67.1
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
20
46.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
33.3
66.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
56
23
0
12
0
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
67
0
0
0
0
0
0
56
0
% D
% Glu:
0
12
0
12
0
0
0
0
0
0
0
0
0
12
0
% E
% Phe:
0
0
0
0
56
0
0
0
0
12
0
23
0
23
0
% F
% Gly:
0
0
78
0
0
56
12
0
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
56
% H
% Ile:
34
0
0
0
0
0
0
12
12
0
0
0
0
12
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% K
% Leu:
0
78
12
0
0
0
0
12
23
0
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
12
0
12
0
0
56
0
78
12
56
0
23
% P
% Gln:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
12
0
0
0
0
12
0
0
0
0
0
% R
% Ser:
0
0
0
12
0
12
0
67
0
12
0
0
23
0
0
% S
% Thr:
0
0
0
0
0
12
12
12
0
67
12
67
0
0
0
% T
% Val:
56
12
0
12
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _