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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C12orf53 All Species: 22.12
Human Site: T247 Identified Species: 60.83
UniProt: Q8IYJ0 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IYJ0 NP_710152.1 282 30076 T247 G A F G D S P T P T P D H E E
Chimpanzee Pan troglodytes XP_508963 343 35546 T308 G A F G D S P T P T P D H E E
Rhesus Macaque Macaca mulatta XP_001107986 276 29408 T247 G A F G D S P T P T P D H E E
Dog Lupus familis XP_854420 210 22341 F201 L V A T G I I F K F W I P L V
Cat Felis silvestris
Mouse Mus musculus Q6P1B3 278 29725 T243 G A F G D S P T P T P D H E E
Rat Rattus norvegicus Q5U2P6 272 29114 T243 G A F G D S P T P T P D H E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518109 222 23445 R213 G E A P A T L R P F L F G T R
Chicken Gallus gallus XP_416507 304 33214 T267 G P Y S D S L T P T S E A E E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001074455 187 21076 S178 D S R Q T L H S T P S F P D R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.3 97.8 71.9 N.A. 92.9 91.8 N.A. 20.9 60.2 N.A. 23 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 81.9 97.8 73 N.A. 93.9 92.1 N.A. 29.4 67.1 N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. 13.3 53.3 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 0 N.A. 100 100 N.A. 20 66.6 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 56 23 0 12 0 0 0 0 0 0 0 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 0 67 0 0 0 0 0 0 56 0 12 0 % D
% Glu: 0 12 0 0 0 0 0 0 0 0 0 12 0 67 67 % E
% Phe: 0 0 56 0 0 0 0 12 0 23 0 23 0 0 0 % F
% Gly: 78 0 0 56 12 0 0 0 0 0 0 0 12 0 0 % G
% His: 0 0 0 0 0 0 12 0 0 0 0 0 56 0 0 % H
% Ile: 0 0 0 0 0 12 12 0 0 0 0 12 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % K
% Leu: 12 0 0 0 0 12 23 0 0 0 12 0 0 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 12 0 12 0 0 56 0 78 12 56 0 23 0 0 % P
% Gln: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 12 0 0 0 0 12 0 0 0 0 0 0 23 % R
% Ser: 0 12 0 12 0 67 0 12 0 0 23 0 0 0 0 % S
% Thr: 0 0 0 12 12 12 0 67 12 67 0 0 0 12 0 % T
% Val: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % W
% Tyr: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _