KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC105
All Species:
12.42
Human Site:
T374
Identified Species:
34.17
UniProt:
Q8IYK2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYK2
NP_775753.2
499
56923
T374
Y
N
Q
E
L
Y
T
T
H
G
L
I
K
G
P
Chimpanzee
Pan troglodytes
XP_512448
516
57467
T378
Y
N
Q
E
L
Y
T
T
H
G
L
I
K
G
P
Rhesus Macaque
Macaca mulatta
XP_001112667
229
26077
L120
L
H
R
K
A
R
A
L
Q
T
T
E
V
V
H
Dog
Lupus familis
XP_853075
229
26221
L120
M
H
R
D
A
R
A
L
Q
T
A
E
V
V
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4K7
499
57227
T374
F
N
Q
E
M
Y
V
T
R
G
I
I
K
G
P
Rat
Rattus norvegicus
Q4V7B5
500
57447
T374
F
N
Q
E
M
Y
V
T
R
G
L
I
K
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517097
188
21770
V78
W
R
F
R
M
E
L
V
K
G
G
G
M
L
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693940
461
51489
K347
T
R
Q
A
I
Y
R
K
Q
R
Q
M
Q
C
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780678
448
49844
R337
H
S
I
H
R
A
Q
R
W
Y
D
S
T
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.3
44
39.6
N.A.
78.1
78
N.A.
21.8
N.A.
N.A.
25.6
N.A.
N.A.
N.A.
N.A.
23
Protein Similarity:
100
79.2
45.4
42
N.A.
86.7
86.5
N.A.
27.2
N.A.
N.A.
42.2
N.A.
N.A.
N.A.
N.A.
40.2
P-Site Identity:
100
100
0
0
N.A.
66.6
73.3
N.A.
6.6
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
20
20
N.A.
86.6
86.6
N.A.
20
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
23
12
23
0
0
0
12
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
0
0
0
12
0
0
0
0
0
0
12
0
0
0
0
% D
% Glu:
0
0
0
45
0
12
0
0
0
0
0
23
0
12
12
% E
% Phe:
23
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
56
12
12
0
45
0
% G
% His:
12
23
0
12
0
0
0
0
23
0
0
0
0
0
23
% H
% Ile:
0
0
12
0
12
0
0
0
0
0
12
45
0
0
0
% I
% Lys:
0
0
0
12
0
0
0
12
12
0
0
0
45
0
12
% K
% Leu:
12
0
0
0
23
0
12
23
0
0
34
0
0
12
0
% L
% Met:
12
0
0
0
34
0
0
0
0
0
0
12
12
0
0
% M
% Asn:
0
45
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
45
% P
% Gln:
0
0
56
0
0
0
12
0
34
0
12
0
12
0
0
% Q
% Arg:
0
23
23
12
12
23
12
12
23
12
0
0
0
0
0
% R
% Ser:
0
12
0
0
0
0
0
0
0
0
0
12
0
0
0
% S
% Thr:
12
0
0
0
0
0
23
45
0
23
12
0
12
0
0
% T
% Val:
0
0
0
0
0
0
23
12
0
0
0
0
23
23
0
% V
% Trp:
12
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% W
% Tyr:
23
0
0
0
0
56
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _