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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC105
All Species:
6.36
Human Site:
T488
Identified Species:
17.5
UniProt:
Q8IYK2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYK2
NP_775753.2
499
56923
T488
V
K
D
W
D
P
R
T
P
P
P
R
S
K
S
Chimpanzee
Pan troglodytes
XP_512448
516
57467
L493
L
H
N
S
P
H
C
L
R
A
E
I
S
A
A
Rhesus Macaque
Macaca mulatta
XP_001112667
229
26077
K219
K
M
E
K
D
M
E
K
S
E
V
L
L
K
V
Dog
Lupus familis
XP_853075
229
26221
K219
K
M
E
K
D
M
E
K
S
E
A
L
L
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4K7
499
57227
T488
V
N
D
W
D
P
P
T
P
A
R
S
Q
T
N
Rat
Rattus norvegicus
Q4V7B5
500
57447
T488
I
N
D
W
D
P
R
T
P
P
P
C
S
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517097
188
21770
C178
G
I
L
I
N
Q
Q
C
K
K
L
R
S
Y
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693940
461
51489
L446
V
D
S
A
V
V
R
L
R
R
R
L
V
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780678
448
49844
L438
I
V
R
G
R
R
R
L
A
N
H
R
W
V
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.3
44
39.6
N.A.
78.1
78
N.A.
21.8
N.A.
N.A.
25.6
N.A.
N.A.
N.A.
N.A.
23
Protein Similarity:
100
79.2
45.4
42
N.A.
86.7
86.5
N.A.
27.2
N.A.
N.A.
42.2
N.A.
N.A.
N.A.
N.A.
40.2
P-Site Identity:
100
6.6
13.3
13.3
N.A.
46.6
66.6
N.A.
13.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
20
20
N.A.
53.3
86.6
N.A.
26.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
0
12
23
12
0
0
12
12
% A
% Cys:
0
0
0
0
0
0
12
12
0
0
0
12
0
0
0
% C
% Asp:
0
12
34
0
56
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
23
0
0
0
23
0
0
23
12
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
12
0
0
0
12
0
0
0
0
12
0
0
0
0
% H
% Ile:
23
12
0
12
0
0
0
0
0
0
0
12
0
0
0
% I
% Lys:
23
12
0
23
0
0
0
23
12
12
0
0
0
34
0
% K
% Leu:
12
0
12
0
0
0
0
34
0
0
12
34
23
0
0
% L
% Met:
0
23
0
0
0
23
0
0
0
0
0
0
0
0
12
% M
% Asn:
0
23
12
0
12
0
0
0
0
12
0
0
0
0
12
% N
% Pro:
0
0
0
0
12
34
12
0
34
23
23
0
0
0
12
% P
% Gln:
0
0
0
0
0
12
12
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
12
0
12
12
45
0
23
12
23
34
0
23
12
% R
% Ser:
0
0
12
12
0
0
0
0
23
0
0
12
45
0
12
% S
% Thr:
0
0
0
0
0
0
0
34
0
0
0
0
0
12
12
% T
% Val:
34
12
0
0
12
12
0
0
0
0
12
0
12
12
23
% V
% Trp:
0
0
0
34
0
0
0
0
0
0
0
0
12
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _