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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC105
All Species:
13.64
Human Site:
Y401
Identified Species:
37.5
UniProt:
Q8IYK2
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYK2
NP_775753.2
499
56923
Y401
D
R
P
L
V
R
M
Y
Q
R
H
V
G
T
Q
Chimpanzee
Pan troglodytes
XP_512448
516
57467
Y405
D
R
P
L
V
R
M
Y
Q
R
H
V
G
T
Q
Rhesus Macaque
Macaca mulatta
XP_001112667
229
26077
I147
L
G
R
A
Q
H
Q
I
N
G
R
V
R
Q
L
Dog
Lupus familis
XP_853075
229
26221
I147
L
C
R
A
Q
H
Q
I
N
G
Q
L
R
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4K7
499
57227
Y401
N
R
P
L
V
R
M
Y
Q
R
H
V
G
T
Q
Rat
Rattus norvegicus
Q4V7B5
500
57447
Y401
N
R
P
L
V
R
M
Y
Q
R
H
V
G
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517097
188
21770
W105
G
K
I
K
P
P
A
W
K
S
R
L
P
L
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693940
461
51489
E374
R
A
D
L
F
C
R
E
R
L
N
R
P
M
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780678
448
49844
L364
D
L
E
T
R
E
K
L
T
R
P
I
V
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.3
44
39.6
N.A.
78.1
78
N.A.
21.8
N.A.
N.A.
25.6
N.A.
N.A.
N.A.
N.A.
23
Protein Similarity:
100
79.2
45.4
42
N.A.
86.7
86.5
N.A.
27.2
N.A.
N.A.
42.2
N.A.
N.A.
N.A.
N.A.
40.2
P-Site Identity:
100
100
6.6
0
N.A.
93.3
93.3
N.A.
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
6.6
6.6
N.A.
100
100
N.A.
26.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
23
0
0
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
12
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
12
0
0
12
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
12
0
0
0
0
0
0
0
23
0
0
45
0
0
% G
% His:
0
0
0
0
0
23
0
0
0
0
45
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
0
23
0
0
0
12
0
0
0
% I
% Lys:
0
12
0
12
0
0
12
0
12
0
0
0
0
0
0
% K
% Leu:
23
12
0
56
0
0
0
12
0
12
0
23
0
23
23
% L
% Met:
0
0
0
0
0
0
45
0
0
0
0
0
0
12
0
% M
% Asn:
23
0
0
0
0
0
0
0
23
0
12
0
0
0
0
% N
% Pro:
0
0
45
0
12
12
0
0
0
0
12
0
23
0
12
% P
% Gln:
0
0
0
0
23
0
23
0
45
0
12
0
0
12
45
% Q
% Arg:
12
45
23
0
12
45
12
0
12
56
23
12
23
12
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% S
% Thr:
0
0
0
12
0
0
0
0
12
0
0
0
0
45
12
% T
% Val:
0
0
0
0
45
0
0
0
0
0
0
56
12
0
12
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
45
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _