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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C4orf23
All Species:
9.7
Human Site:
S631
Identified Species:
17.78
UniProt:
Q8IYL2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYL2
NP_689757
757
84629
S631
K
Q
L
N
T
R
S
S
R
N
G
S
L
K
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118752
757
84219
S631
K
Q
L
N
T
G
S
S
R
N
G
S
L
K
T
Dog
Lupus familis
XP_545909
707
79384
A580
E
Q
I
S
I
G
D
A
S
S
S
S
S
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2Q2
713
79865
S587
K
K
F
N
T
G
N
S
E
A
R
S
L
K
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505248
529
59450
G412
V
A
G
W
S
R
A
G
D
V
S
A
H
R
S
Chicken
Gallus gallus
XP_420816
661
74622
N538
C
S
N
S
H
G
G
N
E
D
T
W
N
P
G
Frog
Xenopus laevis
Q4KLT3
668
76749
Q538
K
E
T
P
I
T
D
Q
S
E
T
V
W
N
T
Zebra Danio
Brachydanio rerio
NP_001006086
340
38618
D223
K
V
W
P
E
V
T
D
P
Q
K
F
V
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHB9
521
59366
T404
E
E
S
V
R
N
C
T
Q
V
D
K
T
I
I
Honey Bee
Apis mellifera
XP_393767
463
53693
S346
N
I
V
N
I
V
S
S
Q
L
L
H
E
G
C
Nematode Worm
Caenorhab. elegans
Q45EK7
563
64854
I446
P
V
T
D
R
E
R
I
A
K
K
L
F
D
F
Sea Urchin
Strong. purpuratus
XP_788093
625
70353
D508
G
D
A
A
K
L
F
D
G
P
T
L
K
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SE80
515
57926
P398
D
E
L
T
P
W
T
P
I
L
A
A
I
S
D
Conservation
Percent
Protein Identity:
100
N.A.
92.3
69
N.A.
67.2
N.A.
N.A.
32.3
56.6
51.9
25.6
N.A.
29.4
29.8
24.8
35.4
Protein Similarity:
100
N.A.
94.9
77.5
N.A.
77.4
N.A.
N.A.
43.5
67.2
65.7
34
N.A.
44.6
41.8
41.2
50.9
P-Site Identity:
100
N.A.
93.3
20
N.A.
46.6
N.A.
N.A.
6.6
0
13.3
6.6
N.A.
0
20
0
0
P-Site Similarity:
100
N.A.
93.3
53.3
N.A.
60
N.A.
N.A.
40
20
20
20
N.A.
26.6
33.3
6.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
0
8
8
8
8
8
16
0
0
8
% A
% Cys:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% C
% Asp:
8
8
0
8
0
0
16
16
8
8
8
0
0
8
8
% D
% Glu:
16
24
0
0
8
8
0
0
16
8
0
0
8
0
8
% E
% Phe:
0
0
8
0
0
0
8
0
0
0
0
8
8
8
8
% F
% Gly:
8
0
8
0
0
31
8
8
8
0
16
0
0
8
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
8
8
0
0
% H
% Ile:
0
8
8
0
24
0
0
8
8
0
0
0
8
8
8
% I
% Lys:
39
8
0
0
8
0
0
0
0
8
16
8
8
31
0
% K
% Leu:
0
0
24
0
0
8
0
0
0
16
8
16
24
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
31
0
8
8
8
0
16
0
0
8
16
0
% N
% Pro:
8
0
0
16
8
0
0
8
8
8
0
0
0
8
8
% P
% Gln:
0
24
0
0
0
0
0
8
16
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
16
16
8
0
16
0
8
0
0
8
0
% R
% Ser:
0
8
8
16
8
0
24
31
16
8
16
31
8
8
8
% S
% Thr:
0
0
16
8
24
8
16
8
0
0
24
0
8
0
24
% T
% Val:
8
16
8
8
0
16
0
0
0
16
0
8
8
0
0
% V
% Trp:
0
0
8
8
0
8
0
0
0
0
0
8
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _