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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C4orf23
All Species:
13.33
Human Site:
S646
Identified Species:
24.44
UniProt:
Q8IYL2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYL2
NP_689757
757
84629
S646
W
N
G
G
E
S
L
S
L
A
E
V
A
N
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118752
757
84219
S646
W
N
R
G
E
S
L
S
L
A
E
V
A
S
E
Dog
Lupus familis
XP_545909
707
79384
S595
W
N
R
G
G
S
L
S
L
T
E
V
A
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2Q2
713
79865
S602
W
N
G
G
G
S
L
S
L
A
E
V
A
A
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505248
529
59450
T427
P
A
P
S
Q
A
V
T
P
V
L
S
A
R
T
Chicken
Gallus gallus
XP_420816
661
74622
V553
E
S
L
S
L
K
E
V
A
E
H
L
N
K
E
Frog
Xenopus laevis
Q4KLT3
668
76749
E553
G
R
S
L
T
L
R
E
V
A
E
H
L
H
A
Zebra Danio
Brachydanio rerio
NP_001006086
340
38618
L238
D
V
A
I
A
T
Y
L
L
V
L
W
A
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHB9
521
59366
F419
D
G
L
V
F
K
I
F
K
L
I
L
D
S
N
Honey Bee
Apis mellifera
XP_393767
463
53693
P361
T
I
Y
I
E
E
T
P
K
K
F
W
N
A
G
Nematode Worm
Caenorhab. elegans
Q45EK7
563
64854
V461
V
L
N
Y
S
D
A
V
R
D
G
W
R
C
G
Sea Urchin
Strong. purpuratus
XP_788093
625
70353
K523
K
S
E
C
G
G
L
K
T
L
L
K
N
Y
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SE80
515
57926
C413
C
P
F
I
M
I
P
C
C
S
H
D
L
T
G
Conservation
Percent
Protein Identity:
100
N.A.
92.3
69
N.A.
67.2
N.A.
N.A.
32.3
56.6
51.9
25.6
N.A.
29.4
29.8
24.8
35.4
Protein Similarity:
100
N.A.
94.9
77.5
N.A.
77.4
N.A.
N.A.
43.5
67.2
65.7
34
N.A.
44.6
41.8
41.2
50.9
P-Site Identity:
100
N.A.
86.6
73.3
N.A.
86.6
N.A.
N.A.
6.6
6.6
13.3
20
N.A.
0
6.6
0
6.6
P-Site Similarity:
100
N.A.
93.3
80
N.A.
86.6
N.A.
N.A.
33.3
20
26.6
26.6
N.A.
20
6.6
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
8
8
8
0
8
31
0
0
47
16
8
% A
% Cys:
8
0
0
8
0
0
0
8
8
0
0
0
0
8
0
% C
% Asp:
16
0
0
0
0
8
0
0
0
8
0
8
8
0
0
% D
% Glu:
8
0
8
0
24
8
8
8
0
8
39
0
0
8
47
% E
% Phe:
0
0
8
0
8
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
8
8
16
31
24
8
0
0
0
0
8
0
0
0
24
% G
% His:
0
0
0
0
0
0
0
0
0
0
16
8
0
8
0
% H
% Ile:
0
8
0
24
0
8
8
0
0
0
8
0
0
0
0
% I
% Lys:
8
0
0
0
0
16
0
8
16
8
0
8
0
8
0
% K
% Leu:
0
8
16
8
8
8
39
8
39
16
24
16
16
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
31
8
0
0
0
0
0
0
0
0
0
24
8
16
% N
% Pro:
8
8
8
0
0
0
8
8
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
16
0
0
0
8
0
8
0
0
0
8
8
0
% R
% Ser:
0
16
8
16
8
31
0
31
0
8
0
8
0
24
0
% S
% Thr:
8
0
0
0
8
8
8
8
8
8
0
0
0
8
8
% T
% Val:
8
8
0
8
0
0
8
16
8
16
0
31
0
0
0
% V
% Trp:
31
0
0
0
0
0
0
0
0
0
0
24
0
0
0
% W
% Tyr:
0
0
8
8
0
0
8
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _