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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C4orf23 All Species: 6.36
Human Site: Y264 Identified Species: 11.67
UniProt: Q8IYL2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IYL2 NP_689757 757 84629 Y264 W H S D G I V Y P K P T W L G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001118752 757 84219 Y264 W H S D G I V Y P K P T W L G
Dog Lupus familis XP_545909 707 79384 G227 Y P R P S W L G E E L L A R L
Cat Felis silvestris
Mouse Mus musculus Q9D2Q2 713 79865 G227 Y P K P A W L G E E L L S K L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505248 529 59450 T101 L A E W S V R T D A G E F K S
Chicken Gallus gallus XP_420816 661 74622 L227 Y S K I Y Q D L K E K Y K E M
Frog Xenopus laevis Q4KLT3 668 76749 Y227 Y Q N L K E K Y R D M V K V W
Zebra Danio Brachydanio rerio NP_001006086 340 38618
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VHB9 521 59366 C93 G I V D F E N C L Y E C Q F A
Honey Bee Apis mellifera XP_393767 463 53693 K35 S I E W L K K K L L P C I L K
Nematode Worm Caenorhab. elegans Q45EK7 563 64854 I135 P Y S I A I K I P T D T S I Q
Sea Urchin Strong. purpuratus XP_788093 625 70353 D197 G Y P G K G I D L R R R K I W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SE80 515 57926 N87 D T E K N I Q N G L E T P L S
Conservation
Percent
Protein Identity: 100 N.A. 92.3 69 N.A. 67.2 N.A. N.A. 32.3 56.6 51.9 25.6 N.A. 29.4 29.8 24.8 35.4
Protein Similarity: 100 N.A. 94.9 77.5 N.A. 77.4 N.A. N.A. 43.5 67.2 65.7 34 N.A. 44.6 41.8 41.2 50.9
P-Site Identity: 100 N.A. 100 0 N.A. 0 N.A. N.A. 0 0 6.6 0 N.A. 6.6 13.3 26.6 0
P-Site Similarity: 100 N.A. 100 20 N.A. 20 N.A. N.A. 13.3 13.3 26.6 0 N.A. 6.6 13.3 40 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 20.4
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 32.1
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 20
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 16 0 0 0 0 8 0 0 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 16 0 0 0 % C
% Asp: 8 0 0 24 0 0 8 8 8 8 8 0 0 0 0 % D
% Glu: 0 0 24 0 0 16 0 0 16 24 16 8 0 8 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 8 8 0 % F
% Gly: 16 0 0 8 16 8 0 16 8 0 8 0 0 0 16 % G
% His: 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 16 0 16 0 31 8 8 0 0 0 0 8 16 0 % I
% Lys: 0 0 16 8 16 8 24 8 8 16 8 0 24 16 8 % K
% Leu: 8 0 0 8 8 0 16 8 24 16 16 16 0 31 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % M
% Asn: 0 0 8 0 8 0 8 8 0 0 0 0 0 0 0 % N
% Pro: 8 16 8 16 0 0 0 0 24 0 24 0 8 0 0 % P
% Gln: 0 8 0 0 0 8 8 0 0 0 0 0 8 0 8 % Q
% Arg: 0 0 8 0 0 0 8 0 8 8 8 8 0 8 0 % R
% Ser: 8 8 24 0 16 0 0 0 0 0 0 0 16 0 16 % S
% Thr: 0 8 0 0 0 0 0 8 0 8 0 31 0 0 0 % T
% Val: 0 0 8 0 0 8 16 0 0 0 0 8 0 8 0 % V
% Trp: 16 0 0 16 0 16 0 0 0 0 0 0 16 0 16 % W
% Tyr: 31 16 0 0 8 0 0 24 0 8 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _