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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C1orf174
All Species:
10.61
Human Site:
S196
Identified Species:
25.93
UniProt:
Q8IYL3
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYL3
NP_997239.2
243
25977
S196
S
N
Q
P
M
P
V
S
R
F
F
G
N
V
E
Chimpanzee
Pan troglodytes
XP_513745
290
30562
S243
S
N
Q
P
M
P
V
S
R
F
F
G
N
V
E
Rhesus Macaque
Macaca mulatta
XP_001085085
244
25951
S196
S
N
Q
P
M
P
V
S
R
F
F
G
N
V
E
Dog
Lupus familis
XP_536724
239
25595
F196
P
M
P
V
G
R
F
F
G
N
V
E
L
M
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q80WR5
230
24756
M196
F
F
G
N
V
E
L
M
Q
D
L
P
P
A
S
Rat
Rattus norvegicus
Q5M951
222
23649
P193
E
L
M
Q
D
L
P
P
A
S
S
S
C
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515744
229
24559
S198
M
Q
D
L
P
P
V
S
A
P
Y
T
L
M
S
Chicken
Gallus gallus
XP_417541
220
23729
V191
I
Q
D
Q
P
A
A
V
L
P
S
T
T
M
S
Frog
Xenopus laevis
Q3KQW6
205
22715
E176
C
A
S
M
S
R
R
E
F
R
N
L
H
F
R
Zebra Danio
Brachydanio rerio
Q1L9C7
189
20766
R160
D
V
V
E
D
Y
P
R
R
T
P
G
S
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82
94.6
64.6
N.A.
65
63.7
N.A.
39.5
27.5
37
27.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
82.4
96.7
74.9
N.A.
74.4
72.8
N.A.
52.6
47.7
53
46
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
0
0
N.A.
20
0
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
20
0
N.A.
33.3
6.6
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
10
0
20
0
0
0
0
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
10
0
20
0
20
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
10
0
0
10
0
10
0
10
0
0
0
10
0
0
30
% E
% Phe:
10
10
0
0
0
0
10
10
10
30
30
0
0
10
0
% F
% Gly:
0
0
10
0
10
0
0
0
10
0
0
40
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
10
0
10
0
10
10
0
10
0
10
10
20
0
0
% L
% Met:
10
10
10
10
30
0
0
10
0
0
0
0
0
30
0
% M
% Asn:
0
30
0
10
0
0
0
0
0
10
10
0
30
0
0
% N
% Pro:
10
0
10
30
20
40
20
10
0
20
10
10
10
10
0
% P
% Gln:
0
20
30
20
0
0
0
0
10
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
20
10
10
40
10
0
0
0
0
20
% R
% Ser:
30
0
10
0
10
0
0
40
0
10
20
10
10
0
40
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
20
10
0
0
% T
% Val:
0
10
10
10
10
0
40
10
0
0
10
0
0
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _