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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR65
All Species:
18.18
Human Site:
Y174
Identified Species:
44.44
UniProt:
Q8IYL9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYL9
NP_003599.2
337
39333
Y174
F
T
L
C
Y
D
K
Y
P
L
E
K
W
Q
I
Chimpanzee
Pan troglodytes
XP_523005
337
39341
Y174
F
T
L
C
Y
D
K
Y
P
L
E
K
W
Q
I
Rhesus Macaque
Macaca mulatta
XP_001082670
337
39496
Y174
F
T
L
C
Y
D
R
Y
P
L
E
K
W
Q
I
Dog
Lupus familis
XP_547943
341
39583
Y174
F
T
L
C
Y
D
K
Y
P
L
E
K
W
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61038
337
39370
Y176
F
T
L
C
Y
D
K
Y
P
L
E
K
W
Q
I
Rat
Rattus norvegicus
Q4KLH9
365
41249
W179
E
K
F
P
M
E
R
W
V
A
W
M
N
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511798
340
39378
P183
T
L
C
Y
D
K
Y
P
L
E
I
W
Q
A
N
Chicken
Gallus gallus
P34996
362
41176
L200
D
T
T
A
D
E
Y
L
R
S
Y
F
V
Y
S
Frog
Xenopus laevis
Q2TAD5
363
40901
K196
D
F
S
G
V
S
S
K
E
N
E
N
F
W
I
Zebra Danio
Brachydanio rerio
A5PLE7
368
41686
I187
E
Y
P
N
F
E
K
I
D
N
L
P
V
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.1
83.5
N.A.
79.5
38
N.A.
62.6
26.7
28.6
26
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
98.2
92.3
N.A.
89.9
57.8
N.A.
79.4
46.1
47.3
50.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
100
0
N.A.
0
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
0
13.3
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
10
0
0
0
10
0
% A
% Cys:
0
0
10
50
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
0
20
50
0
0
10
0
0
0
0
0
0
% D
% Glu:
20
0
0
0
0
30
0
0
10
10
60
0
0
0
0
% E
% Phe:
50
10
10
0
10
0
0
0
0
0
0
10
10
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
60
% I
% Lys:
0
10
0
0
0
10
50
10
0
0
0
50
0
0
0
% K
% Leu:
0
10
50
0
0
0
0
10
10
50
10
0
0
10
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
10
0
10
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
20
0
10
10
0
10
% N
% Pro:
0
0
10
10
0
0
0
10
50
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
50
0
% Q
% Arg:
0
0
0
0
0
0
20
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
10
10
0
0
10
0
0
0
0
10
% S
% Thr:
10
60
10
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
10
0
0
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
10
10
50
10
0
% W
% Tyr:
0
10
0
10
50
0
20
50
0
0
10
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _