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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR65 All Species: 18.18
Human Site: Y174 Identified Species: 44.44
UniProt: Q8IYL9 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IYL9 NP_003599.2 337 39333 Y174 F T L C Y D K Y P L E K W Q I
Chimpanzee Pan troglodytes XP_523005 337 39341 Y174 F T L C Y D K Y P L E K W Q I
Rhesus Macaque Macaca mulatta XP_001082670 337 39496 Y174 F T L C Y D R Y P L E K W Q I
Dog Lupus familis XP_547943 341 39583 Y174 F T L C Y D K Y P L E K W Q I
Cat Felis silvestris
Mouse Mus musculus Q61038 337 39370 Y176 F T L C Y D K Y P L E K W Q I
Rat Rattus norvegicus Q4KLH9 365 41249 W179 E K F P M E R W V A W M N L Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511798 340 39378 P183 T L C Y D K Y P L E I W Q A N
Chicken Gallus gallus P34996 362 41176 L200 D T T A D E Y L R S Y F V Y S
Frog Xenopus laevis Q2TAD5 363 40901 K196 D F S G V S S K E N E N F W I
Zebra Danio Brachydanio rerio A5PLE7 368 41686 I187 E Y P N F E K I D N L P V M L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 96.1 83.5 N.A. 79.5 38 N.A. 62.6 26.7 28.6 26 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 98.2 92.3 N.A. 89.9 57.8 N.A. 79.4 46.1 47.3 50.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 100 N.A. 100 0 N.A. 0 6.6 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 0 13.3 20 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 10 0 0 0 10 0 % A
% Cys: 0 0 10 50 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 0 0 0 20 50 0 0 10 0 0 0 0 0 0 % D
% Glu: 20 0 0 0 0 30 0 0 10 10 60 0 0 0 0 % E
% Phe: 50 10 10 0 10 0 0 0 0 0 0 10 10 0 0 % F
% Gly: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 60 % I
% Lys: 0 10 0 0 0 10 50 10 0 0 0 50 0 0 0 % K
% Leu: 0 10 50 0 0 0 0 10 10 50 10 0 0 10 10 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 10 0 10 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 20 0 10 10 0 10 % N
% Pro: 0 0 10 10 0 0 0 10 50 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 50 0 % Q
% Arg: 0 0 0 0 0 0 20 0 10 0 0 0 0 0 0 % R
% Ser: 0 0 10 0 0 10 10 0 0 10 0 0 0 0 10 % S
% Thr: 10 60 10 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 0 0 0 10 0 0 0 20 0 0 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 10 10 50 10 0 % W
% Tyr: 0 10 0 10 50 0 20 50 0 0 10 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _