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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT12
All Species:
24.55
Human Site:
Y137
Identified Species:
49.09
UniProt:
Q8IYM1
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYM1
NP_001147930.1
358
40748
Y137
L
G
Y
I
N
E
Q
Y
E
Q
Y
L
Q
E
E
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
K134
V
I
D
Y
I
D
S
K
F
E
D
Y
L
N
A
Rhesus Macaque
Macaca mulatta
XP_001102088
360
40906
Y152
E
K
Y
I
N
E
Q
Y
E
K
F
L
K
E
E
Dog
Lupus familis
XP_857693
357
40495
Y150
E
K
Y
I
N
E
Q
Y
E
K
F
L
K
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80UG5
583
65556
Y385
M
K
F
I
N
D
Q
Y
E
K
Y
L
Q
E
E
Rat
Rattus norvegicus
Q4V8G5
356
40780
Y135
L
S
Y
I
N
Q
Q
Y
E
Q
Y
L
Q
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505764
436
49083
Y234
M
R
F
I
N
D
Q
Y
E
K
Y
L
Q
E
E
Chicken
Gallus gallus
Q5ZMH1
349
40206
Q124
I
I
Q
Y
I
D
N
Q
F
E
R
Y
L
H
D
Frog
Xenopus laevis
Q9DE33
356
40909
Q124
I
I
S
Y
V
D
N
Q
F
E
R
Y
L
H
D
Zebra Danio
Brachydanio rerio
A2BGU8
361
40623
Y162
S
K
H
I
N
E
Q
Y
E
K
F
L
K
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40797
539
60125
K230
I
L
E
Y
V
D
S
K
Y
E
E
Y
L
T
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25342
322
37006
H122
V
K
Y
I
K
E
Q
H
S
Q
Y
L
R
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.4
54.7
54.7
N.A.
37.5
85.1
N.A.
51.3
39.9
39.9
54.8
N.A.
31.5
N.A.
N.A.
N.A.
Protein Similarity:
100
54.3
74.4
74.3
N.A.
47.3
92.1
N.A.
64.2
58.9
60.3
73.9
N.A.
45.8
N.A.
N.A.
N.A.
P-Site Identity:
100
0
66.6
66.6
N.A.
66.6
86.6
N.A.
66.6
0
0
60
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
86.6
86.6
N.A.
93.3
93.3
N.A.
93.3
26.6
26.6
86.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
50
0
0
0
0
9
0
0
0
17
% D
% Glu:
17
0
9
0
0
42
0
0
59
34
9
0
0
59
67
% E
% Phe:
0
0
17
0
0
0
0
0
25
0
25
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
0
0
0
0
9
0
0
0
0
0
17
0
% H
% Ile:
25
25
0
67
17
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
42
0
0
9
0
0
17
0
42
0
0
25
9
0
% K
% Leu:
17
9
0
0
0
0
0
0
0
0
0
67
34
0
0
% L
% Met:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
59
0
17
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
9
67
17
0
25
0
0
34
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
17
0
9
0
0
% R
% Ser:
9
9
9
0
0
0
17
0
9
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% T
% Val:
17
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
42
34
0
0
0
59
9
0
42
34
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _