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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZDHHC23
All Species:
10.61
Human Site:
S208
Identified Species:
25.93
UniProt:
Q8IYP9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYP9
NP_775841.2
409
45983
S208
G
D
R
S
L
S
S
S
Q
L
E
C
L
S
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100427
402
45318
S201
S
D
R
A
L
S
S
S
Q
L
E
L
L
N
R
Dog
Lupus familis
XP_849643
427
47792
G208
S
E
R
P
G
S
G
G
P
A
E
R
P
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q5Y5T3
425
48132
S198
N
D
K
S
P
S
N
S
Q
I
E
C
P
V
K
Rat
Rattus norvegicus
Q76IC6
429
48440
S202
N
D
K
S
P
S
N
S
Q
I
E
C
P
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521451
448
48968
L245
A
K
E
D
P
G
Y
L
R
R
P
G
E
G
A
Chicken
Gallus gallus
NP_001012837
410
45702
A208
N
G
L
H
G
A
A
A
G
G
H
S
V
N
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003757
425
47971
G209
S
T
P
P
D
V
D
G
V
Y
L
N
G
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785093
436
48769
H217
F
A
D
I
T
H
L
H
K
R
N
N
G
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q52T38
620
68215
F317
G
A
L
A
W
L
G
F
I
L
A
T
A
G
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.5
80.8
N.A.
85.4
84.8
N.A.
55.3
63.6
N.A.
47.7
N.A.
N.A.
N.A.
N.A.
31.6
Protein Similarity:
100
N.A.
96.8
86.4
N.A.
89.8
89.2
N.A.
65.1
75.3
N.A.
66.5
N.A.
N.A.
N.A.
N.A.
51.8
P-Site Identity:
100
N.A.
73.3
20
N.A.
46.6
46.6
N.A.
0
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
86.6
26.6
N.A.
73.3
73.3
N.A.
6.6
33.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
0
20
0
10
10
10
0
10
10
0
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
30
0
0
0
% C
% Asp:
0
40
10
10
10
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
10
0
0
0
0
0
0
0
50
0
10
0
0
% E
% Phe:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
20
10
0
0
20
10
20
20
10
10
0
10
20
30
10
% G
% His:
0
0
0
10
0
10
0
10
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
10
20
0
0
0
10
0
% I
% Lys:
0
10
20
0
0
0
0
0
10
0
0
0
0
0
20
% K
% Leu:
0
0
20
0
20
10
10
10
0
30
10
10
20
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
30
0
0
0
0
0
20
0
0
0
10
20
0
20
0
% N
% Pro:
0
0
10
20
30
0
0
0
10
0
10
0
30
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% Q
% Arg:
0
0
30
0
0
0
0
0
10
20
0
10
0
0
30
% R
% Ser:
30
0
0
30
0
50
20
40
0
0
0
10
0
20
10
% S
% Thr:
0
10
0
0
10
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
10
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _