KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZDHHC23
All Species:
10.91
Human Site:
S252
Identified Species:
26.67
UniProt:
Q8IYP9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYP9
NP_775841.2
409
45983
S252
S
S
K
M
P
A
G
S
P
T
K
A
K
E
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100427
402
45318
S245
S
S
R
M
P
A
G
S
P
T
K
A
K
E
D
Dog
Lupus familis
XP_849643
427
47792
W252
P
A
K
V
K
E
D
W
C
A
K
C
Q
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q5Y5T3
425
48132
S242
S
S
R
V
G
L
D
S
P
A
K
V
K
E
D
Rat
Rattus norvegicus
Q76IC6
429
48440
S246
S
S
R
V
G
L
D
S
P
A
K
S
K
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521451
448
48968
R289
P
A
R
A
G
H
C
R
L
C
R
V
C
V
R
Chicken
Gallus gallus
NP_001012837
410
45702
L252
A
R
A
G
H
C
R
L
C
G
R
C
V
R
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003757
425
47971
K253
R
N
W
C
A
V
C
K
V
V
R
P
R
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785093
436
48769
I261
T
N
E
T
E
G
S
I
P
T
D
W
C
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q52T38
620
68215
N361
L
L
K
I
E
L
N
N
P
A
L
L
A
G
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.5
80.8
N.A.
85.4
84.8
N.A.
55.3
63.6
N.A.
47.7
N.A.
N.A.
N.A.
N.A.
31.6
Protein Similarity:
100
N.A.
96.8
86.4
N.A.
89.8
89.2
N.A.
65.1
75.3
N.A.
66.5
N.A.
N.A.
N.A.
N.A.
51.8
P-Site Identity:
100
N.A.
93.3
13.3
N.A.
53.3
53.3
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
100
33.3
N.A.
66.6
73.3
N.A.
20
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
10
10
10
20
0
0
0
40
0
20
10
0
20
% A
% Cys:
0
0
0
10
0
10
20
0
20
10
0
20
20
0
0
% C
% Asp:
0
0
0
0
0
0
30
0
0
0
10
0
0
0
40
% D
% Glu:
0
0
10
0
20
10
0
0
0
0
0
0
0
40
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
30
10
20
0
0
10
0
0
0
10
0
% G
% His:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
30
0
10
0
0
10
0
0
50
0
40
0
0
% K
% Leu:
10
10
0
0
0
30
0
10
10
0
10
10
0
10
0
% L
% Met:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
20
0
0
0
0
10
10
0
0
0
0
0
10
10
% N
% Pro:
20
0
0
0
20
0
0
0
60
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
10
10
40
0
0
0
10
10
0
0
30
0
10
20
20
% R
% Ser:
40
40
0
0
0
0
10
40
0
0
0
10
0
0
0
% S
% Thr:
10
0
0
10
0
0
0
0
0
30
0
0
0
0
0
% T
% Val:
0
0
0
30
0
10
0
0
10
10
0
20
10
10
10
% V
% Trp:
0
0
10
0
0
0
0
10
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _