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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZDHHC23
All Species:
15.15
Human Site:
T221
Identified Species:
37.04
UniProt:
Q8IYP9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYP9
NP_775841.2
409
45983
T221
S
R
K
G
Q
E
K
T
K
G
F
P
G
A
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100427
402
45318
T214
N
R
K
G
Q
E
K
T
K
G
F
P
G
T
D
Dog
Lupus familis
XP_849643
427
47792
A221
G
P
G
G
Q
D
K
A
R
G
P
L
S
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5Y5T3
425
48132
T211
V
K
K
G
Q
E
K
T
K
G
F
P
G
T
D
Rat
Rattus norvegicus
Q76IC6
429
48440
T215
I
K
K
G
Q
E
K
T
K
G
F
P
G
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521451
448
48968
P258
G
A
A
G
S
E
C
P
G
G
Q
P
V
P
V
Chicken
Gallus gallus
NP_001012837
410
45702
S221
N
G
E
T
K
G
Y
S
R
V
L
A
E
E
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003757
425
47971
G222
A
R
H
Q
V
V
I
G
S
R
V
A
S
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785093
436
48769
S230
S
S
N
S
L
Y
E
S
E
E
S
D
S
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q52T38
620
68215
C330
G
L
F
L
F
Y
R
C
S
R
K
D
P
G
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.5
80.8
N.A.
85.4
84.8
N.A.
55.3
63.6
N.A.
47.7
N.A.
N.A.
N.A.
N.A.
31.6
Protein Similarity:
100
N.A.
96.8
86.4
N.A.
89.8
89.2
N.A.
65.1
75.3
N.A.
66.5
N.A.
N.A.
N.A.
N.A.
51.8
P-Site Identity:
100
N.A.
86.6
26.6
N.A.
80
80
N.A.
26.6
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
93.3
46.6
N.A.
86.6
86.6
N.A.
26.6
33.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
0
0
0
10
0
0
0
20
0
10
0
% A
% Cys:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
20
0
0
40
% D
% Glu:
0
0
10
0
0
50
10
0
10
10
0
0
10
10
10
% E
% Phe:
0
0
10
0
10
0
0
0
0
0
40
0
0
0
0
% F
% Gly:
30
10
10
60
0
10
0
10
10
60
0
0
40
10
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
20
40
0
10
0
50
0
40
0
10
0
0
0
0
% K
% Leu:
0
10
0
10
10
0
0
0
0
0
10
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
10
0
0
10
50
10
10
0
% P
% Gln:
0
0
0
10
50
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
30
0
0
0
0
10
0
20
20
0
0
0
0
20
% R
% Ser:
20
10
0
10
10
0
0
20
20
0
10
0
30
30
0
% S
% Thr:
0
0
0
10
0
0
0
40
0
0
0
0
0
30
0
% T
% Val:
10
0
0
0
10
10
0
0
0
10
10
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
20
10
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _