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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD4
All Species:
11.82
Human Site:
S384
Identified Species:
32.5
UniProt:
Q8IYR2
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYR2
NP_443160.2
804
89225
S384
K
D
I
C
L
P
E
S
N
N
Q
V
K
T
L
Chimpanzee
Pan troglodytes
XP_511253
835
92733
S384
K
D
I
C
L
P
E
S
N
N
Q
V
K
T
L
Rhesus Macaque
Macaca mulatta
XP_001117365
802
88688
S384
K
D
I
C
L
P
E
S
D
N
Q
V
K
T
L
Dog
Lupus familis
XP_548315
794
88855
C381
E
I
S
N
K
D
M
C
S
P
E
S
E
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTK5
799
88520
S384
T
D
T
C
L
P
E
S
K
N
L
V
K
A
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3V0
742
82008
V366
F
S
E
V
S
R
L
V
E
W
S
R
D
D
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070062
753
83658
A372
H
V
A
Q
H
S
P
A
S
R
F
L
M
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392262
679
77853
A308
C
Q
T
C
S
C
V
A
Y
C
S
I
S
C
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781331
704
78496
N335
Y
L
D
S
G
L
V
N
Y
E
C
I
V
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
91.2
74.5
N.A.
71.8
N.A.
N.A.
N.A.
47.6
N.A.
36.8
N.A.
N.A.
22.6
N.A.
26.1
Protein Similarity:
100
95.5
95.2
84.5
N.A.
82.2
N.A.
N.A.
N.A.
62.1
N.A.
54.3
N.A.
N.A.
39.7
N.A.
43.1
P-Site Identity:
100
100
93.3
6.6
N.A.
60
N.A.
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
33.3
N.A.
60
N.A.
N.A.
N.A.
0
N.A.
26.6
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
23
0
0
0
0
0
23
0
% A
% Cys:
12
0
0
56
0
12
0
12
0
12
12
0
0
12
0
% C
% Asp:
0
45
12
0
0
12
0
0
12
0
0
0
12
12
0
% D
% Glu:
12
0
12
0
0
0
45
0
12
12
12
0
12
0
0
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
12
% F
% Gly:
0
0
0
0
12
0
0
0
0
0
0
0
0
12
0
% G
% His:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
34
0
0
0
0
0
0
0
0
23
0
0
12
% I
% Lys:
34
0
0
0
12
0
0
0
12
0
0
0
45
0
0
% K
% Leu:
0
12
0
0
45
12
12
0
0
0
12
12
0
0
56
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
12
0
0
0
12
23
45
0
0
0
12
0
% N
% Pro:
0
0
0
0
0
45
12
0
0
12
0
0
0
0
0
% P
% Gln:
0
12
0
12
0
0
0
0
0
0
34
0
0
0
0
% Q
% Arg:
0
0
0
0
0
12
0
0
0
12
0
12
0
0
12
% R
% Ser:
0
12
12
12
23
12
0
45
23
0
23
12
12
0
12
% S
% Thr:
12
0
23
0
0
0
0
0
0
0
0
0
0
34
0
% T
% Val:
0
12
0
12
0
0
23
12
0
0
0
45
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _