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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD4
All Species:
19.7
Human Site:
S56
Identified Species:
54.17
UniProt:
Q8IYR2
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYR2
NP_443160.2
804
89225
S56
E
L
F
L
K
R
L
S
K
G
Y
L
V
G
K
Chimpanzee
Pan troglodytes
XP_511253
835
92733
S56
E
L
F
L
K
R
L
S
K
G
Y
L
V
G
K
Rhesus Macaque
Macaca mulatta
XP_001117365
802
88688
S56
E
L
F
L
K
R
L
S
K
G
Y
L
V
G
K
Dog
Lupus familis
XP_548315
794
88855
S56
E
M
F
L
N
N
L
S
R
G
Y
F
V
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTK5
799
88520
S56
E
M
F
L
K
E
L
S
S
S
Y
S
V
E
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3V0
742
82008
C54
E
A
A
L
Q
R
L
C
R
R
A
R
T
G
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070062
753
83658
S56
L
N
I
L
S
R
I
S
E
K
F
S
V
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392262
679
77853
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781331
704
78496
T24
L
L
Q
I
L
N
S
T
V
D
H
C
I
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
91.2
74.5
N.A.
71.8
N.A.
N.A.
N.A.
47.6
N.A.
36.8
N.A.
N.A.
22.6
N.A.
26.1
Protein Similarity:
100
95.5
95.2
84.5
N.A.
82.2
N.A.
N.A.
N.A.
62.1
N.A.
54.3
N.A.
N.A.
39.7
N.A.
43.1
P-Site Identity:
100
100
100
66.6
N.A.
60
N.A.
N.A.
N.A.
40
N.A.
33.3
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
66.6
N.A.
N.A.
N.A.
53.3
N.A.
53.3
N.A.
N.A.
0
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
0
0
0
0
0
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
12
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% D
% Glu:
67
0
0
0
0
12
0
0
12
0
0
0
0
23
0
% E
% Phe:
0
0
56
0
0
0
0
0
0
0
12
12
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
45
0
0
0
56
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
12
12
0
0
12
0
0
0
0
0
12
0
0
% I
% Lys:
0
0
0
0
45
0
0
0
34
12
0
0
0
12
78
% K
% Leu:
23
45
0
78
12
0
67
0
0
0
0
34
0
0
0
% L
% Met:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
12
23
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
56
0
0
23
12
0
12
0
0
0
% R
% Ser:
0
0
0
0
12
0
12
67
12
12
0
23
0
0
12
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
0
0
12
0
0
% T
% Val:
0
0
0
0
0
0
0
0
12
0
0
0
67
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
56
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _