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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD4
All Species:
11.21
Human Site:
T174
Identified Species:
30.83
UniProt:
Q8IYR2
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYR2
NP_443160.2
804
89225
T174
S
D
L
E
R
N
F
T
A
T
P
A
L
A
D
Chimpanzee
Pan troglodytes
XP_511253
835
92733
T174
S
D
L
E
R
N
F
T
A
T
P
A
L
A
D
Rhesus Macaque
Macaca mulatta
XP_001117365
802
88688
T174
G
D
L
E
R
N
F
T
A
T
P
T
L
A
D
Dog
Lupus familis
XP_548315
794
88855
A174
R
D
L
E
S
N
F
A
A
K
P
T
L
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTK5
799
88520
T174
S
D
L
E
S
S
L
T
A
K
P
T
L
V
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3V0
742
82008
D162
G
R
L
Q
D
A
T
D
T
L
T
A
V
E
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070062
753
83658
P165
K
A
E
K
P
N
I
P
H
T
D
H
Q
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392262
679
77853
Q104
N
A
V
L
L
A
P
Q
K
D
V
G
I
V
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781331
704
78496
D131
L
D
S
I
T
G
E
D
K
K
R
Q
E
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
91.2
74.5
N.A.
71.8
N.A.
N.A.
N.A.
47.6
N.A.
36.8
N.A.
N.A.
22.6
N.A.
26.1
Protein Similarity:
100
95.5
95.2
84.5
N.A.
82.2
N.A.
N.A.
N.A.
62.1
N.A.
54.3
N.A.
N.A.
39.7
N.A.
43.1
P-Site Identity:
100
100
86.6
60
N.A.
53.3
N.A.
N.A.
N.A.
13.3
N.A.
13.3
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
86.6
60
N.A.
60
N.A.
N.A.
N.A.
33.3
N.A.
20
N.A.
N.A.
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
0
0
0
23
0
12
56
0
0
34
0
45
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
67
0
0
12
0
0
23
0
12
12
0
0
0
34
% D
% Glu:
0
0
12
56
0
0
12
0
0
0
0
0
12
12
0
% E
% Phe:
0
0
0
0
0
0
45
0
0
0
0
0
0
0
0
% F
% Gly:
23
0
0
0
0
12
0
0
0
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
12
0
0
12
0
0
0
% H
% Ile:
0
0
0
12
0
0
12
0
0
0
0
0
12
12
0
% I
% Lys:
12
0
0
12
0
0
0
0
23
34
0
0
0
0
12
% K
% Leu:
12
0
67
12
12
0
12
0
0
12
0
0
56
12
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
56
0
0
0
0
0
0
0
0
12
% N
% Pro:
0
0
0
0
12
0
12
12
0
0
56
0
0
0
0
% P
% Gln:
0
0
0
12
0
0
0
12
0
0
0
12
12
0
0
% Q
% Arg:
12
12
0
0
34
0
0
0
0
0
12
0
0
0
0
% R
% Ser:
34
0
12
0
23
12
0
0
0
0
0
0
0
0
12
% S
% Thr:
0
0
0
0
12
0
12
45
12
45
12
34
0
0
0
% T
% Val:
0
0
12
0
0
0
0
0
0
0
12
0
12
23
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _