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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD4
All Species:
13.33
Human Site:
T85
Identified Species:
36.67
UniProt:
Q8IYR2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYR2
NP_443160.2
804
89225
T85
K
F
Q
E
K
D
Y
T
G
A
A
V
L
Y
S
Chimpanzee
Pan troglodytes
XP_511253
835
92733
T85
K
F
Q
E
K
D
Y
T
G
A
A
V
L
Y
S
Rhesus Macaque
Macaca mulatta
XP_001117365
802
88688
T85
K
F
Q
E
K
D
Y
T
G
A
A
V
L
Y
S
Dog
Lupus familis
XP_548315
794
88855
V85
K
F
Q
K
K
D
Y
V
G
A
T
V
L
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTK5
799
88520
T85
K
F
Q
E
K
E
Y
T
D
A
A
V
L
Y
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3V0
742
82008
R83
Q
F
G
R
C
C
Y
R
D
A
V
R
L
Y
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070062
753
83658
P85
S
F
K
V
K
D
Y
P
A
A
V
L
H
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392262
679
77853
P26
R
L
Q
N
A
I
T
P
Q
D
M
K
K
F
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781331
704
78496
R53
A
S
S
A
E
D
S
R
Q
K
G
N
E
L
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
91.2
74.5
N.A.
71.8
N.A.
N.A.
N.A.
47.6
N.A.
36.8
N.A.
N.A.
22.6
N.A.
26.1
Protein Similarity:
100
95.5
95.2
84.5
N.A.
82.2
N.A.
N.A.
N.A.
62.1
N.A.
54.3
N.A.
N.A.
39.7
N.A.
43.1
P-Site Identity:
100
100
100
80
N.A.
86.6
N.A.
N.A.
N.A.
40
N.A.
46.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
N.A.
N.A.
N.A.
46.6
N.A.
60
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
12
12
0
0
0
12
78
45
0
0
0
0
% A
% Cys:
0
0
0
0
12
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
67
0
0
23
12
0
0
0
0
0
% D
% Glu:
0
0
0
45
12
12
0
0
0
0
0
0
12
0
0
% E
% Phe:
0
78
0
0
0
0
0
0
0
0
0
0
0
12
12
% F
% Gly:
0
0
12
0
0
0
0
0
45
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% I
% Lys:
56
0
12
12
67
0
0
0
0
12
0
12
12
0
0
% K
% Leu:
0
12
0
0
0
0
0
0
0
0
0
12
67
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
23
0
0
0
0
0
0
0
% P
% Gln:
12
0
67
0
0
0
0
0
23
0
0
0
0
0
0
% Q
% Arg:
12
0
0
12
0
0
0
23
0
0
0
12
0
0
0
% R
% Ser:
12
12
12
0
0
0
12
0
0
0
0
0
0
0
78
% S
% Thr:
0
0
0
0
0
0
12
45
0
0
12
0
0
0
0
% T
% Val:
0
0
0
12
0
0
0
12
0
0
23
56
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
78
0
0
0
0
0
0
78
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _