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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRAMD1C
All Species:
12.73
Human Site:
S181
Identified Species:
28
UniProt:
Q8IYS0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYS0
NP_060047.3
662
76035
S181
Q
N
V
L
L
D
K
S
L
T
R
Q
E
F
W
Chimpanzee
Pan troglodytes
XP_516656
750
85818
S269
Q
N
V
L
L
D
K
S
L
T
R
Q
E
F
W
Rhesus Macaque
Macaca mulatta
XP_001108370
738
85457
P208
Q
N
A
L
L
E
K
P
L
C
P
K
E
L
W
Dog
Lupus familis
XP_849625
677
78203
S195
Q
N
V
L
L
D
K
S
L
T
R
Q
E
F
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI52
457
52185
Rat
Rattus norvegicus
Q3KR56
723
80666
T205
Q
N
A
L
L
E
K
T
L
S
P
R
E
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520923
581
66969
R113
R
S
Y
L
S
I
F
R
L
W
Q
N
V
L
L
Chicken
Gallus gallus
XP_416574
697
80439
R216
Q
N
V
L
L
D
K
R
L
T
K
Q
E
F
W
Frog
Xenopus laevis
NP_001084725
458
52027
Zebra Danio
Brachydanio rerio
XP_688384
692
79396
K195
Q
N
V
L
M
E
K
K
L
T
K
L
E
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394943
746
84382
P276
Q
N
A
L
I
G
E
P
M
N
A
P
E
L
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
39.8
85.2
N.A.
54.8
37.9
N.A.
65.4
59.9
35.3
42.3
N.A.
N.A.
30.5
N.A.
N.A.
Protein Similarity:
100
88.1
58.1
90.9
N.A.
63.2
55.1
N.A.
74.9
75.4
49
61.8
N.A.
N.A.
48.9
N.A.
N.A.
P-Site Identity:
100
100
53.3
100
N.A.
0
53.3
N.A.
13.3
86.6
0
53.3
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
100
100
66.6
100
N.A.
0
80
N.A.
33.3
93.3
0
73.3
N.A.
N.A.
53.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
28
0
0
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
37
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
28
10
0
0
0
0
0
73
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
37
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
64
10
0
0
19
10
0
0
0
% K
% Leu:
0
0
0
82
55
0
0
0
73
0
0
10
0
46
19
% L
% Met:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
73
0
0
0
0
0
0
0
10
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
19
0
0
19
10
0
0
0
% P
% Gln:
73
0
0
0
0
0
0
0
0
0
10
37
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
19
0
0
28
10
0
0
0
% R
% Ser:
0
10
0
0
10
0
0
28
0
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
46
0
0
0
0
0
% T
% Val:
0
0
46
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
64
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _