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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRAMD1C All Species: 6.36
Human Site: S295 Identified Species: 14
UniProt: Q8IYS0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IYS0 NP_060047.3 662 76035 S295 L T R V P S K S L D L N K N E
Chimpanzee Pan troglodytes XP_516656 750 85818 S383 L T R V P S K S L D L N K N E
Rhesus Macaque Macaca mulatta XP_001108370 738 85457 D322 L E K E L A I D N I M G E K I
Dog Lupus familis XP_849625 677 78203 K309 R L R R M P S K S L D L N K N
Cat Felis silvestris
Mouse Mus musculus Q8CI52 457 52185 K103 N E Y L S L D K S S T S D S V
Rat Rattus norvegicus Q3KR56 723 80666 P319 T V T P V A E P L S A E P A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520923 581 66969 S227 K K S P L L T S E R R P S G A
Chicken Gallus gallus XP_416574 697 80439 L330 S R S L E K S L D L N E N E N
Frog Xenopus laevis NP_001084725 458 52027 D104 G N E N Q H F D R S S L S D S
Zebra Danio Brachydanio rerio XP_688384 692 79396 S309 P N L S L N R S G S E R V S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394943 746 84382 P390 G T I V C T S P H E G R Q I G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.7 39.8 85.2 N.A. 54.8 37.9 N.A. 65.4 59.9 35.3 42.3 N.A. N.A. 30.5 N.A. N.A.
Protein Similarity: 100 88.1 58.1 90.9 N.A. 63.2 55.1 N.A. 74.9 75.4 49 61.8 N.A. N.A. 48.9 N.A. N.A.
P-Site Identity: 100 100 6.6 6.6 N.A. 0 6.6 N.A. 6.6 0 0 6.6 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 100 100 33.3 6.6 N.A. 20 20 N.A. 6.6 6.6 6.6 33.3 N.A. N.A. 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 19 0 0 0 0 10 0 0 10 10 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 19 10 19 10 0 10 10 0 % D
% Glu: 0 19 10 10 10 0 10 0 10 10 10 19 10 10 19 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 19 0 0 0 0 0 0 0 10 0 10 10 0 10 10 % G
% His: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 10 0 0 10 0 0 0 10 10 % I
% Lys: 10 10 10 0 0 10 19 19 0 0 0 0 19 19 10 % K
% Leu: 28 10 10 19 28 19 0 10 28 19 19 19 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 10 19 0 10 0 10 0 0 10 0 10 19 19 19 19 % N
% Pro: 10 0 0 19 19 10 0 19 0 0 0 10 10 0 10 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 10 10 28 10 0 0 10 0 10 10 10 19 0 0 0 % R
% Ser: 10 0 19 10 10 19 28 37 19 37 10 10 19 19 10 % S
% Thr: 10 28 10 0 0 10 10 0 0 0 10 0 0 0 0 % T
% Val: 0 10 0 28 10 0 0 0 0 0 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _