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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA2013
All Species:
21.82
Human Site:
Y617
Identified Species:
48
UniProt:
Q8IYS2
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYS2
NP_612355.1
634
69157
Y617
F
K
L
I
Y
N
E
Y
C
G
P
G
A
K
P
Chimpanzee
Pan troglodytes
XP_001143405
634
69111
Y617
F
K
L
I
Y
N
E
Y
C
G
P
G
A
K
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535403
634
69119
Y617
F
K
L
I
Y
N
E
Y
C
G
P
G
A
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91X21
634
69407
Y617
F
K
L
I
Y
N
E
Y
C
G
P
G
A
K
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518364
308
34464
C292
K
L
I
Y
N
E
Y
C
G
P
G
A
K
P
L
Chicken
Gallus gallus
XP_425754
450
50454
Y434
L
F
L
F
K
L
I
Y
N
E
Y
C
G
P
G
Frog
Xenopus laevis
Q6DDG2
604
68503
Y588
L
F
L
F
K
L
I
Y
N
E
Y
C
G
P
G
Zebra Danio
Brachydanio rerio
NP_001107084
606
68311
Y589
F
K
L
I
Y
N
E
Y
C
G
P
G
A
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608635
637
72416
H612
C
A
I
I
I
V
F
H
I
F
L
C
K
L
I
Honey Bee
Apis mellifera
XP_395752
607
69968
N591
F
L
C
K
L
I
I
N
E
Y
H
G
H
Q
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790917
627
70933
Y607
V
K
M
I
W
N
E
Y
C
R
D
R
D
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
94.3
N.A.
91.9
N.A.
N.A.
39.9
50.1
56.3
54.5
N.A.
26.2
26
N.A.
27.9
Protein Similarity:
100
99.8
N.A.
95.4
N.A.
95.9
N.A.
N.A.
44
58.9
70.3
67.9
N.A.
43.7
44
N.A.
46
P-Site Identity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
0
13.3
13.3
100
N.A.
6.6
13.3
N.A.
40
P-Site Similarity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
6.6
13.3
13.3
100
N.A.
20
20
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
10
46
0
0
% A
% Cys:
10
0
10
0
0
0
0
10
55
0
0
28
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
10
% D
% Glu:
0
0
0
0
0
10
55
0
10
19
0
0
0
0
0
% E
% Phe:
55
19
0
19
0
0
10
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
46
10
55
19
10
19
% G
% His:
0
0
0
0
0
0
0
10
0
0
10
0
10
0
0
% H
% Ile:
0
0
19
64
10
10
28
0
10
0
0
0
0
0
10
% I
% Lys:
10
55
0
10
19
0
0
0
0
0
0
0
19
46
0
% K
% Leu:
19
19
64
0
10
19
0
0
0
0
10
0
0
10
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
55
0
10
19
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
46
0
0
28
46
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
46
0
10
73
0
10
19
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _