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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KATNAL2 All Species: 7.58
Human Site: S442 Identified Species: 11.9
UniProt: Q8IYT4 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IYT4 NP_112593.2 538 61253 S442 W L P P V S K S R A L E L H T
Chimpanzee Pan troglodytes XP_001148241 519 58972 S423 W L P P V S K S R A L E L H T
Rhesus Macaque Macaca mulatta XP_001085922 466 52447 Y381 E L R T E L E Y S V L S Q E T
Dog Lupus familis XP_547587 496 55364 E412 R A L E L R T E L E Y G V L S
Cat Felis silvestris
Mouse Mus musculus Q9D3R6 539 61135 N443 W L P P V S K N H A L E L H T
Rat Rattus norvegicus Q6E0V2 491 55825 A407 L A D D V N L A S I A E N M E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q1HGK7 492 56020 A408 L A D D V D L A N I A E K M E
Frog Xenopus laevis Q3B8D5 505 56809 Y420 E L R M D L D Y S T L G E E T
Zebra Danio Brachydanio rerio Q5U3S1 488 54873 T404 V A S D V D L T V F A E K I E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34808 472 51721 D388 S D E I N Y D D L A A R T E G
Sea Urchin Strong. purpuratus O61577 516 57575 L420 E Q L L R I N L K E V P L A D
Poplar Tree Populus trichocarpa XP_002332658 314 35502 V230 M L P Y D L L V E R T E G F S
Maize Zea mays NP_001168630 398 44561 V314 E I P Y D V L V E K T E G Y S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEX2 523 57218 L426 K A L I N I N L R T V E V A S
Baker's Yeast Sacchar. cerevisiae P52917 437 48154 K353 A L M Q P I R K I Q S A T H F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.7 84 78.8 N.A. 85.9 36.2 N.A. N.A. 36 67.6 36.7 N.A. N.A. N.A. 29.5 31.9
Protein Similarity: 100 96 84.9 83.2 N.A. 91 55.7 N.A. N.A. 55 78.8 55 N.A. N.A. N.A. 50 50.7
P-Site Identity: 100 100 20 0 N.A. 86.6 13.3 N.A. N.A. 13.3 20 13.3 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 100 100 26.6 20 N.A. 93.3 26.6 N.A. N.A. 20 20 20 N.A. N.A. N.A. 6.6 20
Percent
Protein Identity: 35.5 40.5 N.A. 32.5 33.6 N.A.
Protein Similarity: 47.4 55.5 N.A. 53.1 51.1 N.A.
P-Site Identity: 20 13.3 N.A. 13.3 13.3 N.A.
P-Site Similarity: 26.6 33.3 N.A. 33.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 34 0 0 0 0 0 14 0 27 27 7 0 14 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 14 20 20 14 14 7 0 0 0 0 0 0 7 % D
% Glu: 27 0 7 7 7 0 7 7 14 14 0 60 7 20 20 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 0 0 7 7 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 14 14 0 7 % G
% His: 0 0 0 0 0 0 0 0 7 0 0 0 0 27 0 % H
% Ile: 0 7 0 14 0 20 0 0 7 14 0 0 0 7 0 % I
% Lys: 7 0 0 0 0 0 20 7 7 7 0 0 14 0 0 % K
% Leu: 14 47 20 7 7 20 34 14 14 0 34 0 27 7 0 % L
% Met: 7 0 7 7 0 0 0 0 0 0 0 0 0 14 0 % M
% Asn: 0 0 0 0 14 7 14 7 7 0 0 0 7 0 0 % N
% Pro: 0 0 34 20 7 0 0 0 0 0 0 7 0 0 0 % P
% Gln: 0 7 0 7 0 0 0 0 0 7 0 0 7 0 0 % Q
% Arg: 7 0 14 0 7 7 7 0 20 7 0 7 0 0 0 % R
% Ser: 7 0 7 0 0 20 0 14 20 0 7 7 0 0 27 % S
% Thr: 0 0 0 7 0 0 7 7 0 14 14 0 14 0 34 % T
% Val: 7 0 0 0 40 7 0 14 7 7 14 0 14 0 0 % V
% Trp: 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 14 0 7 0 14 0 0 7 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _