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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KATNAL2 All Species: 10.61
Human Site: S454 Identified Species: 16.67
UniProt: Q8IYT4 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IYT4 NP_112593.2 538 61253 S454 L H T E L E Y S V L S Q E T E
Chimpanzee Pan troglodytes XP_001148241 519 58972 S435 L H T E L E Y S V L S Q E T E
Rhesus Macaque Macaca mulatta XP_001085922 466 52447 G393 Q E T E G Y S G S D I K L V C
Dog Lupus familis XP_547587 496 55364 P424 V L S Q V G C P G G S A C R P
Cat Felis silvestris
Mouse Mus musculus Q9D3R6 539 61135 S455 L H T Q L E Y S V L S Q E T E
Rat Rattus norvegicus Q6E0V2 491 55825 A419 N M E G Y S G A D I T N V C R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q1HGK7 492 56020 A420 K M E G Y S G A D I T N V C R
Frog Xenopus laevis Q3B8D5 505 56809 G432 E E T D G Y S G S D I R L V C
Zebra Danio Brachydanio rerio Q5U3S1 488 54873 A416 K I E G Y S G A D I T N V C R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34808 472 51721 D400 T E G F S G A D V V S L C R T
Sea Urchin Strong. purpuratus O61577 516 57575 K432 L A D D I D L K S I A E K M D
Poplar Tree Populus trichocarpa XP_002332658 314 35502 R242 G F S G S D I R L L C K E A A
Maize Zea mays NP_001168630 398 44561 R326 G Y S G S D I R L V C K E A A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEX2 523 57218 E438 V A S D V N I E D V A R R T E
Baker's Yeast Sacchar. cerevisiae P52917 437 48154 T365 T H F K D V S T E D D E T R K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.7 84 78.8 N.A. 85.9 36.2 N.A. N.A. 36 67.6 36.7 N.A. N.A. N.A. 29.5 31.9
Protein Similarity: 100 96 84.9 83.2 N.A. 91 55.7 N.A. N.A. 55 78.8 55 N.A. N.A. N.A. 50 50.7
P-Site Identity: 100 100 13.3 6.6 N.A. 93.3 0 N.A. N.A. 0 6.6 0 N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: 100 100 20 33.3 N.A. 100 20 N.A. N.A. 20 20 20 N.A. N.A. N.A. 20 60
Percent
Protein Identity: 35.5 40.5 N.A. 32.5 33.6 N.A.
Protein Similarity: 47.4 55.5 N.A. 53.1 51.1 N.A.
P-Site Identity: 13.3 6.6 N.A. 13.3 6.6 N.A.
P-Site Similarity: 40 46.6 N.A. 60 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 0 0 0 0 7 20 0 0 14 7 0 14 14 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 14 0 14 20 14 % C
% Asp: 0 0 7 20 7 20 0 7 27 20 7 0 0 0 7 % D
% Glu: 7 20 20 20 0 20 0 7 7 0 0 14 34 0 27 % E
% Phe: 0 7 7 7 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 14 0 7 34 14 14 20 14 7 7 0 0 0 0 0 % G
% His: 0 27 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 7 0 20 0 0 27 14 0 0 0 0 % I
% Lys: 14 0 0 7 0 0 0 7 0 0 0 20 7 0 7 % K
% Leu: 27 7 0 0 20 0 7 0 14 27 0 7 14 0 0 % L
% Met: 0 14 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 7 0 0 0 0 7 0 0 0 0 0 20 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 7 % P
% Gln: 7 0 0 14 0 0 0 0 0 0 0 20 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 14 0 0 0 14 7 20 20 % R
% Ser: 0 0 27 0 20 20 20 20 20 0 34 0 0 0 0 % S
% Thr: 14 0 34 0 0 0 0 7 0 0 20 0 7 27 7 % T
% Val: 14 0 0 0 14 7 0 0 27 20 0 0 20 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 20 14 20 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _