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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HACE1
All Species:
21.21
Human Site:
S385
Identified Species:
46.67
UniProt:
Q8IYU2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYU2
NP_065822.2
909
102342
S385
L
M
K
N
K
R
D
S
T
E
I
T
S
I
L
Chimpanzee
Pan troglodytes
XP_518654
909
102309
S385
L
M
K
N
K
R
D
S
T
E
I
T
S
I
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_854232
909
102021
S385
L
M
K
N
K
K
D
S
T
D
I
T
S
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3U0D9
909
102095
S385
L
M
K
N
K
E
D
S
T
D
I
T
S
I
L
Rat
Rattus norvegicus
NP_001102009
909
102140
S385
L
M
K
N
K
E
D
S
A
D
I
T
S
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506045
1055
117889
S531
L
M
K
N
K
R
D
S
A
D
I
T
S
L
F
Chicken
Gallus gallus
NP_001026249
636
71705
L183
H
K
T
T
V
Q
C
L
L
D
S
G
A
D
I
Frog
Xenopus laevis
Q6DCL5
944
106566
I420
N
K
R
D
S
S
N
I
A
C
I
L
L
K
Q
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
R312
I
R
N
T
A
T
G
R
V
Y
F
V
D
H
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0H4
949
107948
Q456
N
Q
R
Y
L
Y
S
Q
Q
Q
Q
Q
P
T
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301117
471
53841
I18
G
S
S
H
D
Y
S
I
T
V
S
E
V
E
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
98.3
N.A.
97.1
96.9
N.A.
81.9
47.8
87.1
26.2
N.A.
24.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
N.A.
99.2
N.A.
98.7
98.9
N.A.
84
56.4
91.2
43.5
N.A.
40.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
86.6
80
N.A.
73.3
0
6.6
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
86.6
N.A.
86.6
26.6
26.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
36.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
28
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
10
10
0
55
0
0
46
0
0
10
10
10
% D
% Glu:
0
0
0
0
0
19
0
0
0
19
0
10
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% F
% Gly:
10
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% G
% His:
10
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
0
0
0
0
0
19
0
0
64
0
0
46
10
% I
% Lys:
0
19
55
0
55
10
0
0
0
0
0
0
0
10
0
% K
% Leu:
55
0
0
0
10
0
0
10
10
0
0
10
10
10
46
% L
% Met:
0
55
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
0
10
55
0
0
10
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
10
0
0
0
10
0
10
10
10
10
10
0
0
10
% Q
% Arg:
0
10
19
0
0
28
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
0
10
10
19
55
0
0
19
0
55
0
0
% S
% Thr:
0
0
10
19
0
10
0
0
46
0
0
55
0
10
0
% T
% Val:
0
0
0
0
10
0
0
0
10
10
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
19
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _