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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HACE1
All Species:
16.67
Human Site:
Y416
Identified Species:
36.67
UniProt:
Q8IYU2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYU2
NP_065822.2
909
102342
Y416
E
P
P
G
P
G
S
Y
E
N
L
S
T
G
T
Chimpanzee
Pan troglodytes
XP_518654
909
102309
Y416
E
P
P
G
P
G
S
Y
E
N
L
S
T
G
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_854232
909
102021
Y416
E
P
P
G
P
G
S
Y
E
N
L
S
S
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3U0D9
909
102095
Y416
E
P
P
G
P
G
S
Y
E
S
L
P
P
G
P
Rat
Rattus norvegicus
NP_001102009
909
102140
Y416
E
P
P
G
P
G
S
Y
E
R
L
S
T
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506045
1055
117889
R562
F
D
P
R
S
G
S
R
E
N
L
S
I
D
S
Chicken
Gallus gallus
NP_001026249
636
71705
Q214
H
G
Q
R
D
T
A
Q
I
L
L
M
R
G
A
Frog
Xenopus laevis
Q6DCL5
944
106566
H451
G
E
S
G
N
H
D
H
L
L
A
S
T
R
A
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
N343
L
V
L
N
P
S
P
N
G
S
R
A
A
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0H4
949
107948
I487
P
D
G
W
E
K
K
I
Q
S
D
N
R
V
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301117
471
53841
F49
V
D
E
K
H
A
A
F
V
K
F
S
E
K
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
98.3
N.A.
97.1
96.9
N.A.
81.9
47.8
87.1
26.2
N.A.
24.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
N.A.
99.2
N.A.
98.7
98.9
N.A.
84
56.4
91.2
43.5
N.A.
40.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
73.3
86.6
N.A.
46.6
13.3
20
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
80
86.6
N.A.
53.3
20
26.6
20
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
36.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
19
0
0
0
10
10
10
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
28
0
0
10
0
10
0
0
0
10
0
0
10
0
% D
% Glu:
46
10
10
0
10
0
0
0
55
0
0
0
10
0
10
% E
% Phe:
10
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% F
% Gly:
10
10
10
55
0
55
0
0
10
0
0
0
0
55
0
% G
% His:
10
0
0
0
10
10
0
10
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
10
10
0
0
0
10
0
0
% I
% Lys:
0
0
0
10
0
10
10
0
0
10
0
0
0
10
0
% K
% Leu:
10
0
10
0
0
0
0
0
10
19
64
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
10
10
0
0
10
0
37
0
10
0
0
0
% N
% Pro:
10
46
55
0
55
0
10
0
0
0
0
10
10
0
19
% P
% Gln:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
19
0
0
0
10
0
10
10
0
19
10
0
% R
% Ser:
0
0
10
0
10
10
55
0
0
28
0
64
10
0
10
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
37
0
28
% T
% Val:
10
10
0
0
0
0
0
0
10
0
0
0
0
19
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
46
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _