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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHA1
All Species:
4.55
Human Site:
S54
Identified Species:
9.09
UniProt:
Q8IYU8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYU8
NP_689939.1
434
49666
S54
A
G
A
A
W
H
H
S
R
V
S
V
A
A
R
Chimpanzee
Pan troglodytes
XP_001150674
434
49672
S54
A
G
A
A
W
H
H
S
R
V
N
V
A
A
R
Rhesus Macaque
Macaca mulatta
XP_001089388
434
49698
H52
A
G
V
G
A
A
W
H
H
S
R
V
N
V
A
Dog
Lupus familis
XP_543170
433
49545
H53
S
T
G
V
V
W
Y
H
G
R
K
N
V
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CD10
432
49457
W51
L
A
G
A
G
A
A
W
H
H
G
R
V
K
A
Rat
Rattus norvegicus
Q99P63
432
49423
W51
L
A
G
A
G
A
A
W
H
H
G
R
V
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518962
508
58533
Q104
A
L
V
R
R
L
S
Q
K
E
V
E
D
A
L
Chicken
Gallus gallus
XP_417140
433
49577
G54
G
S
V
A
V
C
Y
G
S
W
G
R
P
G
T
Frog
Xenopus laevis
NP_001090059
430
49121
L49
T
V
C
S
G
A
L
L
L
T
G
T
K
L
R
Zebra Danio
Brachydanio rerio
A4IG32
489
55907
I111
E
K
K
K
K
Q
R
I
G
F
R
D
R
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732455
479
54942
K69
A
A
L
A
A
F
I
K
L
R
S
A
E
N
P
Honey Bee
Apis mellifera
XP_392106
461
54367
L50
A
T
F
S
I
A
L
L
V
G
Y
K
Y
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
93
83.6
N.A.
85.9
85.2
N.A.
55.5
62.9
60.5
24.3
N.A.
34.8
35.1
N.A.
N.A.
Protein Similarity:
100
99.5
95.3
89.6
N.A.
91
90.7
N.A.
66.5
76.7
73
44.9
N.A.
55.9
54.4
N.A.
N.A.
P-Site Identity:
100
93.3
20
6.6
N.A.
6.6
6.6
N.A.
13.3
6.6
6.6
0
N.A.
20
13.3
N.A.
N.A.
P-Site Similarity:
100
100
20
20
N.A.
6.6
6.6
N.A.
20
13.3
13.3
0
N.A.
20
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
25
17
50
17
42
17
0
0
0
0
9
17
34
34
% A
% Cys:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
9
0
9
9
0
0
% E
% Phe:
0
0
9
0
0
9
0
0
0
9
0
0
0
0
0
% F
% Gly:
9
25
25
9
25
0
0
9
17
9
34
0
0
9
0
% G
% His:
0
0
0
0
0
17
17
17
25
17
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
9
9
0
0
0
0
0
0
0
% I
% Lys:
0
9
9
9
9
0
0
9
9
0
9
9
9
25
0
% K
% Leu:
17
9
9
0
0
9
17
17
17
0
0
0
0
17
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
9
9
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% P
% Gln:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
9
0
9
0
17
17
17
25
9
0
34
% R
% Ser:
9
9
0
17
0
0
9
17
9
9
17
0
0
0
0
% S
% Thr:
9
17
0
0
0
0
0
0
0
9
0
9
0
0
9
% T
% Val:
0
9
25
9
17
0
0
0
9
17
9
25
25
9
9
% V
% Trp:
0
0
0
0
17
9
9
17
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
17
0
0
0
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _