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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IZUMO1
All Species:
12.12
Human Site:
S325
Identified Species:
44.44
UniProt:
Q8IYV9
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYV9
NP_872381.2
350
38930
S325
V
I
D
F
I
K
S
S
L
F
G
L
G
S
G
Chimpanzee
Pan troglodytes
XP_001171641
350
38954
S325
V
I
D
F
I
K
S
S
L
F
G
L
G
S
G
Rhesus Macaque
Macaca mulatta
XP_001114117
350
39184
S325
V
I
D
F
I
K
S
S
L
F
G
L
G
S
G
Dog
Lupus familis
XP_854830
269
30334
F245
S
R
A
A
V
T
H
F
R
V
R
G
H
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9J7
397
44867
T325
T
R
L
L
I
L
L
T
L
G
F
V
V
L
V
Rat
Rattus norvegicus
Q6AY06
383
43561
S325
L
V
A
S
V
I
A
S
V
L
H
F
R
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516218
274
30258
Q250
S
V
F
W
A
C
L
Q
G
S
R
S
K
G
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
93.7
40.2
N.A.
46.8
55.8
N.A.
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
95.7
55.4
N.A.
62.2
72
N.A.
42.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
13.3
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
26.6
40
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
29
15
15
0
15
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
43
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% E
% Phe:
0
0
15
43
0
0
0
15
0
43
15
15
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
15
15
43
15
43
15
58
% G
% His:
0
0
0
0
0
0
15
0
0
0
15
0
15
0
0
% H
% Ile:
0
43
0
0
58
15
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
43
0
0
0
0
0
0
15
15
0
% K
% Leu:
15
0
15
15
0
15
29
0
58
15
0
43
0
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% P
% Gln:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% Q
% Arg:
0
29
0
0
0
0
0
0
15
0
29
0
15
0
0
% R
% Ser:
29
0
0
15
0
0
43
58
0
15
0
15
0
43
0
% S
% Thr:
15
0
0
0
0
15
0
15
0
0
0
0
0
0
15
% T
% Val:
43
29
0
0
29
0
0
0
15
15
0
15
15
0
15
% V
% Trp:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _