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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTHD1
All Species:
8.48
Human Site:
S295
Identified Species:
23.33
UniProt:
Q8IYW4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYW4
NP_689725.2
607
67538
S295
P
S
G
Q
R
D
V
S
L
D
K
R
S
D
G
Chimpanzee
Pan troglodytes
XP_001166227
607
67487
S295
P
S
G
Q
T
D
V
S
L
D
K
R
S
D
G
Rhesus Macaque
Macaca mulatta
XP_001099911
608
67494
S295
P
S
G
Q
T
D
V
S
L
D
K
R
S
D
G
Dog
Lupus familis
XP_538363
289
33430
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHU3
595
63453
A282
P
K
K
K
E
A
K
A
C
C
K
P
G
S
H
Rat
Rattus norvegicus
Q4V882
608
65029
E299
P
G
L
R
P
N
T
E
P
S
G
S
S
W
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507459
359
40599
E52
F
S
G
G
S
L
S
E
I
M
N
M
L
W
Q
Chicken
Gallus gallus
NP_001012806
483
52552
N176
G
R
G
S
S
Q
P
N
L
S
T
S
Y
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05785
613
71789
Q296
W
L
D
Q
Q
Q
E
Q
Q
Q
L
A
E
Q
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
92.9
36.2
N.A.
26.6
25.4
N.A.
36.9
30.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
95.5
41.1
N.A.
43.1
40.1
N.A.
45.2
46.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
0
N.A.
13.3
20
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
0
N.A.
26.6
33.3
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
12
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
34
0
0
0
34
0
0
0
34
0
% D
% Glu:
0
0
0
0
12
0
12
23
0
0
0
0
12
0
12
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
12
56
12
0
0
0
0
0
0
12
0
12
0
45
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
12
12
12
0
0
12
0
0
0
45
0
0
0
0
% K
% Leu:
0
12
12
0
0
12
0
0
45
0
12
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
12
0
12
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
12
0
0
12
0
0
0
0
% N
% Pro:
56
0
0
0
12
0
12
0
12
0
0
12
0
0
0
% P
% Gln:
0
0
0
45
12
23
0
12
12
12
0
0
0
12
23
% Q
% Arg:
0
12
0
12
12
0
0
0
0
0
0
34
0
0
0
% R
% Ser:
0
45
0
12
23
0
12
34
0
23
0
23
45
23
0
% S
% Thr:
0
0
0
0
23
0
12
0
0
0
12
0
0
0
0
% T
% Val:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% V
% Trp:
12
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _