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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ENTHD1 All Species: 11.82
Human Site: T169 Identified Species: 32.5
UniProt: Q8IYW4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IYW4 NP_689725.2 607 67538 T169 L G S S N S L T A C T S A P T
Chimpanzee Pan troglodytes XP_001166227 607 67487 T169 L G S S N S L T A C T S A P T
Rhesus Macaque Macaca mulatta XP_001099911 608 67494 T169 L G S S S S L T A R T S A P T
Dog Lupus familis XP_538363 289 33430
Cat Felis silvestris
Mouse Mus musculus Q8CHU3 595 63453 G169 G S N Q I T F G R G S S Q P N
Rat Rattus norvegicus Q4V882 608 65029 T180 R G S P S S Y T S A S S S P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507459 359 40599
Chicken Gallus gallus NP_001012806 483 52552 D66 M I W K R L N D H G K N W R H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q05785 613 71789 H170 Q R T R S N P H D S S P S Y Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 92.9 36.2 N.A. 26.6 25.4 N.A. 36.9 30.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.3 95.5 41.1 N.A. 43.1 40.1 N.A. 45.2 46.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 0 N.A. 13.3 40 N.A. 0 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 0 N.A. 33.3 66.6 N.A. 0 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 34 12 0 0 34 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 23 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 12 12 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % F
% Gly: 12 45 0 0 0 0 0 12 0 23 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 12 12 0 0 0 0 0 12 % H
% Ile: 0 12 0 0 12 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 12 0 0 0 0 0 0 12 0 0 0 0 % K
% Leu: 34 0 0 0 0 12 34 0 0 0 0 0 0 0 0 % L
% Met: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 12 0 23 12 12 0 0 0 0 12 0 0 12 % N
% Pro: 0 0 0 12 0 0 12 0 0 0 0 12 0 56 0 % P
% Gln: 12 0 0 12 0 0 0 0 0 0 0 0 12 0 12 % Q
% Arg: 12 12 0 12 12 0 0 0 12 12 0 0 0 12 12 % R
% Ser: 0 12 45 34 34 45 0 0 12 12 34 56 23 0 0 % S
% Thr: 0 0 12 0 0 12 0 45 0 0 34 0 0 0 34 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 12 0 0 0 0 0 0 0 0 0 12 0 0 % W
% Tyr: 0 0 0 0 0 0 12 0 0 0 0 0 0 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _