KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF168
All Species:
12.73
Human Site:
Y104
Identified Species:
28
UniProt:
Q8IYW5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYW5
NP_689830.2
571
65020
Y104
S
E
E
V
A
D
D
Y
Q
P
V
R
L
L
S
Chimpanzee
Pan troglodytes
XP_001164756
571
65044
Y104
S
E
E
V
A
D
D
Y
Q
P
V
R
L
L
S
Rhesus Macaque
Macaca mulatta
XP_001098468
146
16847
Dog
Lupus familis
XP_545152
570
65205
Y104
P
E
D
V
V
D
D
Y
Q
P
V
R
L
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80XJ2
565
64761
C104
S
K
E
I
I
D
E
C
Q
P
V
R
R
L
S
Rat
Rattus norvegicus
B2RYR0
564
64386
Y104
S
K
E
I
V
D
E
Y
Q
P
V
R
L
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519147
409
45328
Chicken
Gallus gallus
XP_001233498
605
68577
P104
L
E
E
E
I
F
V
P
H
P
Q
H
Q
L
S
Frog
Xenopus laevis
Q6INS5
557
62872
L104
S
D
D
L
A
D
E
L
A
S
C
P
A
P
L
Zebra Danio
Brachydanio rerio
Q7T308
474
53229
N58
L
E
T
V
D
K
S
N
M
C
C
P
L
C
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393681
789
90729
D118
R
S
I
D
L
D
A
D
Y
T
G
T
N
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
22.5
76.5
N.A.
63.9
64
N.A.
29
43.4
39.7
34.3
N.A.
N.A.
21.2
N.A.
N.A.
Protein Similarity:
100
99.6
24.5
84.2
N.A.
75.3
74.9
N.A.
43.2
56.8
55.8
51.1
N.A.
N.A.
41.1
N.A.
N.A.
P-Site Identity:
100
100
0
80
N.A.
60
73.3
N.A.
0
33.3
20
20
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
0
86.6
N.A.
80
93.3
N.A.
0
33.3
46.6
20
N.A.
N.A.
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
28
0
10
0
10
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
10
19
0
0
10
0
% C
% Asp:
0
10
19
10
10
64
28
10
0
0
0
0
0
0
0
% D
% Glu:
0
46
46
10
0
0
28
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% H
% Ile:
0
0
10
19
19
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
19
0
0
0
10
0
0
0
0
0
0
0
10
0
% K
% Leu:
19
0
0
10
10
0
0
10
0
0
0
0
46
55
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% N
% Pro:
10
0
0
0
0
0
0
10
0
55
0
19
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
46
0
10
0
10
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
46
10
0
10
% R
% Ser:
46
10
0
0
0
0
10
0
0
10
0
0
0
0
55
% S
% Thr:
0
0
10
0
0
0
0
0
0
10
0
10
0
0
0
% T
% Val:
0
0
0
37
19
0
10
0
0
0
46
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
37
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _