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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM154A
All Species:
11.82
Human Site:
S254
Identified Species:
32.5
UniProt:
Q8IYX7
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYX7
NP_714918.1
474
54621
S254
L
M
G
E
P
A
K
S
L
K
P
L
A
R
P
Chimpanzee
Pan troglodytes
XP_520502
282
31868
P70
L
K
P
L
A
R
P
P
G
L
D
M
P
F
C
Rhesus Macaque
Macaca mulatta
XP_001109607
477
54858
S257
L
M
G
E
P
A
K
S
L
K
P
L
A
R
P
Dog
Lupus familis
XP_531944
501
57470
S281
L
M
G
E
P
T
K
S
L
K
P
P
A
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BQB6
394
45480
N182
E
D
L
T
T
H
R
N
D
F
Q
G
L
A
G
Rat
Rattus norvegicus
Q6AYP6
462
53247
Y244
L
T
T
H
K
D
S
Y
R
G
L
I
G
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424824
469
53968
Y257
L
T
T
N
K
I
S
Y
K
G
L
A
G
E
P
Frog
Xenopus laevis
NP_001087179
469
54054
S254
A
L
G
E
I
T
K
S
C
K
P
E
H
G
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492403
580
64969
N298
E
I
L
K
G
P
A
N
T
E
M
F
S
G
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.6
93.5
78.6
N.A.
31.4
62.6
N.A.
N.A.
46.4
36.9
N.A.
N.A.
N.A.
N.A.
21.5
N.A.
Protein Similarity:
100
58.6
95.3
84.4
N.A.
48.7
76.1
N.A.
N.A.
64.7
55.4
N.A.
N.A.
N.A.
N.A.
35.8
N.A.
P-Site Identity:
100
6.6
100
80
N.A.
0
13.3
N.A.
N.A.
13.3
40
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
13.3
100
80
N.A.
13.3
20
N.A.
N.A.
13.3
46.6
N.A.
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
23
12
0
0
0
0
12
34
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% C
% Asp:
0
12
0
0
0
12
0
0
12
0
12
0
0
0
0
% D
% Glu:
23
0
0
45
0
0
0
0
0
12
0
12
0
23
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
12
0
12
0
12
0
% F
% Gly:
0
0
45
0
12
0
0
0
12
23
0
12
23
23
12
% G
% His:
0
0
0
12
0
12
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
12
0
0
12
12
0
0
0
0
0
12
0
0
0
% I
% Lys:
0
12
0
12
23
0
45
0
12
45
0
0
0
0
12
% K
% Leu:
67
12
23
12
0
0
0
0
34
12
23
23
12
0
0
% L
% Met:
0
34
0
0
0
0
0
0
0
0
12
12
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
23
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
0
34
12
12
12
0
0
45
12
12
0
56
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
0
0
0
0
12
12
0
12
0
0
0
0
34
0
% R
% Ser:
0
0
0
0
0
0
23
45
0
0
0
0
12
0
12
% S
% Thr:
0
23
23
12
12
23
0
0
12
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
23
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _