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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR135
All Species:
6.67
Human Site:
S445
Identified Species:
14.67
UniProt:
Q8IZ08
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZ08
NP_072093.2
494
51736
S445
L
G
A
C
N
R
M
S
S
S
N
P
A
S
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093960
499
51961
S450
L
G
A
C
S
R
V
S
S
S
N
P
A
S
G
Dog
Lupus familis
XP_851935
470
51517
S427
L
E
V
P
P
S
D
S
G
Q
S
S
G
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQP2
457
49342
V421
S
G
S
G
G
E
V
V
M
W
A
R
K
N
P
Rat
Rattus norvegicus
Q7TQN7
457
49562
V421
S
G
S
G
G
E
V
V
M
W
A
R
K
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517016
252
25871
G217
F
R
H
C
R
V
C
G
T
A
X
X
X
X
G
Chicken
Gallus gallus
XP_426475
318
34515
C283
G
E
V
A
M
W
A
C
K
N
P
A
V
L
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686241
447
50042
A412
P
A
N
G
G
D
V
A
M
W
A
C
K
N
P
Tiger Blowfish
Takifugu rubipres
NP_001027836
444
49512
S409
N
S
H
L
S
S
S
S
P
G
K
G
G
G
G
Fruit Fly
Dros. melanogaster
Q9VCZ3
508
56837
P447
R
D
L
E
F
G
G
P
S
R
R
G
T
N
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_501701
430
49119
L394
N
P
M
F
K
E
M
L
I
K
T
L
R
G
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.5
24.8
N.A.
77.1
77.9
N.A.
26.9
33.4
N.A.
51.8
49.8
20.4
N.A.
21.2
N.A.
Protein Similarity:
100
N.A.
96.1
38
N.A.
80.9
81.5
N.A.
32.3
44.5
N.A.
65.9
63.7
37
N.A.
38.4
N.A.
P-Site Identity:
100
N.A.
86.6
13.3
N.A.
6.6
6.6
N.A.
13.3
0
N.A.
0
13.3
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
N.A.
100
26.6
N.A.
26.6
26.6
N.A.
26.6
6.6
N.A.
20
20
20
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
19
10
0
0
10
10
0
10
28
10
19
10
0
% A
% Cys:
0
0
0
28
0
0
10
10
0
0
0
10
0
0
0
% C
% Asp:
0
10
0
0
0
10
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
19
0
10
0
28
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
10
10
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
10
37
0
28
28
10
10
10
10
10
0
19
19
19
55
% G
% His:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
10
10
10
0
28
0
0
% K
% Leu:
28
0
10
10
0
0
0
10
0
0
0
10
0
10
0
% L
% Met:
0
0
10
0
10
0
19
0
28
0
0
0
0
0
0
% M
% Asn:
19
0
10
0
10
0
0
0
0
10
19
0
0
37
0
% N
% Pro:
10
10
0
10
10
0
0
10
10
0
10
19
0
0
37
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
10
10
0
0
10
19
0
0
0
10
10
19
10
0
0
% R
% Ser:
19
10
19
0
19
19
10
37
28
19
10
10
0
19
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
10
0
10
0
0
% T
% Val:
0
0
19
0
0
10
37
19
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
28
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _