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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR135 All Species: 4.55
Human Site: Y317 Identified Species: 10
UniProt: Q8IZ08 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZ08 NP_072093.2 494 51736 Y317 R V R P V N T Y A R V L R F F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093960 499 51961 Y322 R V R P V N T Y A R V L R F F
Dog Lupus familis XP_851935 470 51517 G299 A A P E G G R G A R G A R G A
Cat Felis silvestris
Mouse Mus musculus Q7TQP2 457 49342 A293 F F S E V R T A T T V L I M I
Rat Rattus norvegicus Q7TQN7 457 49562 A293 F F S E V R T A T T V L I M I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517016 252 25871 L89 A Q A P V L L L V F L P S G P
Chicken Gallus gallus XP_426475 318 34515 V155 E M R T A T T V L I M I V S I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_686241 447 50042 M284 L L R F Y S E M R T A T T V L
Tiger Blowfish Takifugu rubipres NP_001027836 444 49512 L281 P V T T Y A Y L L R F Y S E M
Fruit Fly Dros. melanogaster Q9VCZ3 508 56837 H319 A A L L L E K H L Q I S Q I P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_501701 430 49119 K266 L R Q R V E T K L K K L S E R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 94.5 24.8 N.A. 77.1 77.9 N.A. 26.9 33.4 N.A. 51.8 49.8 20.4 N.A. 21.2 N.A.
Protein Similarity: 100 N.A. 96.1 38 N.A. 80.9 81.5 N.A. 32.3 44.5 N.A. 65.9 63.7 37 N.A. 38.4 N.A.
P-Site Identity: 100 N.A. 100 20 N.A. 26.6 26.6 N.A. 13.3 13.3 N.A. 6.6 13.3 0 N.A. 20 N.A.
P-Site Similarity: 100 N.A. 100 20 N.A. 26.6 26.6 N.A. 20 33.3 N.A. 20 13.3 33.3 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 19 10 0 10 10 0 19 28 0 10 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 28 0 19 10 0 0 0 0 0 0 19 0 % E
% Phe: 19 19 0 10 0 0 0 0 0 10 10 0 0 19 19 % F
% Gly: 0 0 0 0 10 10 0 10 0 0 10 0 0 19 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 10 10 19 10 28 % I
% Lys: 0 0 0 0 0 0 10 10 0 10 10 0 0 0 0 % K
% Leu: 19 10 10 10 10 10 10 19 37 0 10 46 0 0 10 % L
% Met: 0 10 0 0 0 0 0 10 0 0 10 0 0 19 10 % M
% Asn: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 10 28 0 0 0 0 0 0 0 10 0 0 19 % P
% Gln: 0 10 10 0 0 0 0 0 0 10 0 0 10 0 0 % Q
% Arg: 19 10 37 10 0 19 10 0 10 37 0 0 28 0 10 % R
% Ser: 0 0 19 0 0 10 0 0 0 0 0 10 28 10 0 % S
% Thr: 0 0 10 19 0 10 55 0 19 28 0 10 10 0 0 % T
% Val: 0 28 0 0 55 0 0 10 10 0 37 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 19 0 10 19 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _