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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF683 All Species: 4.55
Human Site: S155 Identified Species: 11.11
UniProt: Q8IZ20 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZ20 NP_001108231.1 524 56905 S155 P A F S S H N S S S P P P L Q
Chimpanzee Pan troglodytes XP_001142414 555 60774 S186 P A F S S H N S S S P P P L Q
Rhesus Macaque Macaca mulatta XP_001109031 419 45898 P64 Q N R K S P S P L A F C P C P
Dog Lupus familis XP_544480 492 53144 Q137 R D K R G S G Q L R A G E G A
Cat Felis silvestris
Mouse Mus musculus Q60636 856 95818 N439 P A F I P S Y N A H Y P K F L
Rat Rattus norvegicus XP_002726647 476 52482 D121 S L Y K A S T D I E K L T T K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505433 791 87433 H374 F I P S Y N A H Y P K F L L P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_955809 776 87319 G355 Y P G Y S P A G S M P F Y P N
Tiger Blowfish Takifugu rubipres NP_001027861 785 87126 H360 P P G A L Y P H L V P H H Y T
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391847 995 109272 E610 S S G G C Q I E S S P V Y P N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.5 73.4 64.1 N.A. 24 54.5 N.A. 25.4 N.A. N.A. 25.5 28 N.A. 21.7 N.A. N.A.
Protein Similarity: 100 93.5 75.7 71.7 N.A. 37.1 65.2 N.A. 38.9 N.A. N.A. 38.2 39.7 N.A. 33.5 N.A. N.A.
P-Site Identity: 100 100 13.3 0 N.A. 26.6 0 N.A. 13.3 N.A. N.A. 20 13.3 N.A. 20 N.A. N.A.
P-Site Similarity: 100 100 26.6 0 N.A. 40 20 N.A. 20 N.A. N.A. 20 26.6 N.A. 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 30 0 10 10 0 20 0 10 10 10 0 0 0 10 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 10 0 10 0 % C
% Asp: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 10 0 0 10 0 0 % E
% Phe: 10 0 30 0 0 0 0 0 0 0 10 20 0 10 0 % F
% Gly: 0 0 30 10 10 0 10 10 0 0 0 10 0 10 0 % G
% His: 0 0 0 0 0 20 0 20 0 10 0 10 10 0 0 % H
% Ile: 0 10 0 10 0 0 10 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 10 20 0 0 0 0 0 0 20 0 10 0 10 % K
% Leu: 0 10 0 0 10 0 0 0 30 0 0 10 10 30 10 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 10 20 10 0 0 0 0 0 0 20 % N
% Pro: 40 20 10 0 10 20 10 10 0 10 50 30 30 20 20 % P
% Gln: 10 0 0 0 0 10 0 10 0 0 0 0 0 0 20 % Q
% Arg: 10 0 10 10 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 20 10 0 30 40 30 10 20 40 30 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 0 0 10 10 10 % T
% Val: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 10 10 10 10 10 0 10 0 10 0 20 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _