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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF683 All Species: 4.55
Human Site: S301 Identified Species: 11.11
UniProt: Q8IZ20 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.44
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZ20 NP_001108231.1 524 56905 S301 P A K R V P L S S Q T G T A A
Chimpanzee Pan troglodytes XP_001142414 555 60774 S332 P A K R V P L S S Q T G T A A
Rhesus Macaque Macaca mulatta XP_001109031 419 45898 K210 A L P Y P L K K E N G K I L Y
Dog Lupus familis XP_544480 492 53144 G283 A A R T Y S P G P K S T G R V
Cat Felis silvestris
Mouse Mus musculus Q60636 856 95818 R585 M N L I K N K R N M T G Y K T
Rat Rattus norvegicus XP_002726647 476 52482 Q267 A G H T L Y S Q V G S R S S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505433 791 87433 R520 M N L I K N K R N M S G Y K T
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_955809 776 87319 R501 I N L S K M K R G S T G Y K S
Tiger Blowfish Takifugu rubipres NP_001027861 785 87126 V506 L S K V K P G V G S V G Y K A
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391847 995 109272 Q756 G S L S P N S Q G S R G Y R S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.5 73.4 64.1 N.A. 24 54.5 N.A. 25.4 N.A. N.A. 25.5 28 N.A. 21.7 N.A. N.A.
Protein Similarity: 100 93.5 75.7 71.7 N.A. 37.1 65.2 N.A. 38.9 N.A. N.A. 38.2 39.7 N.A. 33.5 N.A. N.A.
P-Site Identity: 100 100 0 6.6 N.A. 13.3 0 N.A. 6.6 N.A. N.A. 13.3 26.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 100 0 26.6 N.A. 20 26.6 N.A. 20 N.A. N.A. 20 33.3 N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 30 30 0 0 0 0 0 0 0 0 0 0 0 20 30 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 0 0 0 10 10 30 10 10 70 10 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 20 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 30 0 40 0 40 10 0 10 0 10 0 40 0 % K
% Leu: 10 10 40 0 10 10 20 0 0 0 0 0 0 10 0 % L
% Met: 20 0 0 0 0 10 0 0 0 20 0 0 0 0 0 % M
% Asn: 0 30 0 0 0 30 0 0 20 10 0 0 0 0 0 % N
% Pro: 20 0 10 0 20 30 10 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 20 0 20 0 0 0 0 0 % Q
% Arg: 0 0 10 20 0 0 0 30 0 0 10 10 0 20 10 % R
% Ser: 0 20 0 20 0 10 20 20 20 30 30 0 10 10 20 % S
% Thr: 0 0 0 20 0 0 0 0 0 0 40 10 20 0 20 % T
% Val: 0 0 0 10 20 0 0 10 10 0 10 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 10 10 0 0 0 0 0 0 50 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _