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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RASEF All Species: 21.82
Human Site: S365 Identified Species: 43.64
UniProt: Q8IZ41 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZ41 NP_689786.2 740 82879 S365 S A L E N S Y S K F N R S L H
Chimpanzee Pan troglodytes XP_520093 989 110305 S614 S A L E N S Y S K F N R S L H
Rhesus Macaque Macaca mulatta XP_001104352 740 82761 S365 S A L E N S Y S K F N R S L R
Dog Lupus familis XP_541269 751 83654 S376 T A L E N S Y S K F N R S L R
Cat Felis silvestris
Mouse Mus musculus Q5RI75 627 70734 R261 S K L N R S L R I N N I S P G
Rat Rattus norvegicus XP_001067187 709 79502 S335 S A L E N T Y S K L T K S L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511721 743 83385 S365 T A L E N S F S K Q N R S L R
Chicken Gallus gallus XP_417952 297 32431
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A5WW21 663 75839 S297 K M V M E F Q S Y S S H I E M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VP48 388 43018 A22 P G A G G P P A G S A H P D D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22908 656 74591 L290 L A E N H L E L A M I K S E L
Sea Urchin Strong. purpuratus XP_001177439 377 41472 S10 G G E H I V G S S S L D G G R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.1 95.8 85.7 N.A. 69.5 76 N.A. 72.8 20 N.A. 37.4 N.A. 21 N.A. 28.5 22.9
Protein Similarity: 100 74.5 97.4 90.2 N.A. 76.7 83.5 N.A. 83.4 29.7 N.A. 56.6 N.A. 31.6 N.A. 48.2 36.2
P-Site Identity: 100 100 93.3 86.6 N.A. 33.3 66.6 N.A. 73.3 0 N.A. 6.6 N.A. 0 N.A. 13.3 6.6
P-Site Similarity: 100 100 93.3 93.3 N.A. 33.3 80 N.A. 86.6 0 N.A. 20 N.A. 6.6 N.A. 26.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 59 9 0 0 0 0 9 9 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 9 % D
% Glu: 0 0 17 50 9 0 9 0 0 0 0 0 0 17 0 % E
% Phe: 0 0 0 0 0 9 9 0 0 34 0 0 0 0 0 % F
% Gly: 9 17 0 9 9 0 9 0 9 0 0 0 9 9 9 % G
% His: 0 0 0 9 9 0 0 0 0 0 0 17 0 0 17 % H
% Ile: 0 0 0 0 9 0 0 0 9 0 9 9 9 0 0 % I
% Lys: 9 9 0 0 0 0 0 0 50 0 0 17 0 0 0 % K
% Leu: 9 0 59 0 0 9 9 9 0 9 9 0 0 50 9 % L
% Met: 0 9 0 9 0 0 0 0 0 9 0 0 0 0 9 % M
% Asn: 0 0 0 17 50 0 0 0 0 9 50 0 0 0 0 % N
% Pro: 9 0 0 0 0 9 9 0 0 0 0 0 9 9 0 % P
% Gln: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % Q
% Arg: 0 0 0 0 9 0 0 9 0 0 0 42 0 0 42 % R
% Ser: 42 0 0 0 0 50 0 67 9 25 9 0 67 0 0 % S
% Thr: 17 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % T
% Val: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 42 0 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _