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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASEF
All Species:
20.91
Human Site:
S505
Identified Species:
41.82
UniProt:
Q8IZ41
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZ41
NP_689786.2
740
82879
S505
L
D
W
K
P
Q
G
S
V
S
E
G
S
I
V
Chimpanzee
Pan troglodytes
XP_520093
989
110305
S754
L
D
W
K
P
Q
G
S
V
S
E
G
S
I
V
Rhesus Macaque
Macaca mulatta
XP_001104352
740
82761
T505
S
D
W
K
L
Q
G
T
V
S
E
G
S
I
V
Dog
Lupus familis
XP_541269
751
83654
S516
L
D
W
K
P
H
G
S
P
S
E
G
S
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q5RI75
627
70734
S401
A
G
E
G
S
T
L
S
S
S
R
K
P
I
S
Rat
Rattus norvegicus
XP_001067187
709
79502
S475
L
H
G
H
P
Q
G
S
A
G
E
G
S
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511721
743
83385
T505
Q
N
P
N
S
P
T
T
L
L
D
W
K
P
K
Chicken
Gallus gallus
XP_417952
297
32431
K71
E
E
L
N
V
E
K
K
Q
E
M
E
Q
K
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A5WW21
663
75839
S437
V
A
R
S
T
V
G
S
I
S
S
S
L
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VP48
388
43018
G162
Y
D
D
D
Y
N
D
G
W
R
S
Y
R
Y
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22908
656
74591
S430
G
T
I
E
E
K
T
S
L
I
L
D
D
A
H
Sea Urchin
Strong. purpuratus
XP_001177439
377
41472
S150
S
E
P
T
P
S
S
S
P
E
G
Q
R
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.1
95.8
85.7
N.A.
69.5
76
N.A.
72.8
20
N.A.
37.4
N.A.
21
N.A.
28.5
22.9
Protein Similarity:
100
74.5
97.4
90.2
N.A.
76.7
83.5
N.A.
83.4
29.7
N.A.
56.6
N.A.
31.6
N.A.
48.2
36.2
P-Site Identity:
100
100
80
80
N.A.
20
60
N.A.
0
0
N.A.
20
N.A.
6.6
N.A.
6.6
13.3
P-Site Similarity:
100
100
86.6
86.6
N.A.
20
60
N.A.
26.6
20
N.A.
33.3
N.A.
6.6
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
0
0
0
9
0
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
42
9
9
0
0
9
0
0
0
9
9
9
0
9
% D
% Glu:
9
17
9
9
9
9
0
0
0
17
42
9
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
9
9
0
0
50
9
0
9
9
42
0
0
0
% G
% His:
0
9
0
9
0
9
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
9
0
0
0
0
0
9
9
0
0
0
34
0
% I
% Lys:
0
0
0
34
0
9
9
9
0
0
0
9
9
9
9
% K
% Leu:
34
0
9
0
9
0
9
0
17
9
9
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% M
% Asn:
0
9
0
17
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
17
0
42
9
0
0
17
0
0
0
9
9
0
% P
% Gln:
9
0
0
0
0
34
0
0
9
0
0
9
9
0
0
% Q
% Arg:
0
0
9
0
0
0
0
0
0
9
9
0
17
9
9
% R
% Ser:
17
0
0
9
17
9
9
67
9
50
17
9
42
0
9
% S
% Thr:
0
9
0
9
9
9
17
17
0
0
0
0
0
9
0
% T
% Val:
9
0
0
0
9
9
0
0
25
0
0
0
0
9
42
% V
% Trp:
0
0
34
0
0
0
0
0
9
0
0
9
0
0
0
% W
% Tyr:
9
0
0
0
9
0
0
0
0
0
0
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _