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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RASEF All Species: 25.15
Human Site: S690 Identified Species: 50.3
UniProt: Q8IZ41 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZ41 NP_689786.2 740 82879 S690 G A L F C E T S A K D G S N I
Chimpanzee Pan troglodytes XP_520093 989 110305 S939 G A L F C E T S A K D G S N I
Rhesus Macaque Macaca mulatta XP_001104352 740 82761 S690 G A L F C E T S A K D G S N I
Dog Lupus familis XP_541269 751 83654 S701 G A L F C E T S A K D G S N I
Cat Felis silvestris
Mouse Mus musculus Q5RI75 627 70734 G581 C E T S A K D G S N V V E A V
Rat Rattus norvegicus XP_001067187 709 79502 S659 G A L F C E T S A K D G S N V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511721 743 83385 S694 N A L F C E T S A K D G S N I
Chicken Gallus gallus XP_417952 297 32431 E251 E H Q L L F Y E C S A A S G H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A5WW21 663 75839 E617 F C E A S A K E G T N V I E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VP48 388 43018 V342 S A K T G L N V E L S F T A V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22908 656 74591 G610 M E T S A L D G S N I D N A M
Sea Urchin Strong. purpuratus XP_001177439 377 41472 S330 K C D F Y E V S A K T G S N V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.1 95.8 85.7 N.A. 69.5 76 N.A. 72.8 20 N.A. 37.4 N.A. 21 N.A. 28.5 22.9
Protein Similarity: 100 74.5 97.4 90.2 N.A. 76.7 83.5 N.A. 83.4 29.7 N.A. 56.6 N.A. 31.6 N.A. 48.2 36.2
P-Site Identity: 100 100 100 100 N.A. 0 93.3 N.A. 93.3 6.6 N.A. 0 N.A. 6.6 N.A. 0 53.3
P-Site Similarity: 100 100 100 100 N.A. 20 100 N.A. 93.3 6.6 N.A. 6.6 N.A. 20 N.A. 20 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 59 0 9 17 9 0 0 59 0 9 9 0 25 9 % A
% Cys: 9 17 0 0 50 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 17 0 0 0 50 9 0 0 0 % D
% Glu: 9 17 9 0 0 59 0 17 9 0 0 0 9 9 0 % E
% Phe: 9 0 0 59 0 9 0 0 0 0 0 9 0 0 0 % F
% Gly: 42 0 0 0 9 0 0 17 9 0 0 59 0 9 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 9 0 9 0 42 % I
% Lys: 9 0 9 0 0 9 9 0 0 59 0 0 0 0 0 % K
% Leu: 0 0 50 9 9 17 0 0 0 9 0 0 0 0 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 9 0 0 0 0 0 9 0 0 17 9 0 9 59 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 0 0 17 9 0 0 59 17 9 9 0 67 0 0 % S
% Thr: 0 0 17 9 0 0 50 0 0 9 9 0 9 0 0 % T
% Val: 0 0 0 0 0 0 9 9 0 0 9 17 0 0 34 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _