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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRMT2A
All Species:
19.39
Human Site:
S140
Identified Species:
38.79
UniProt:
Q8IZ69
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZ69
NP_073564.3
625
68726
S140
L
W
K
G
R
P
L
S
V
R
L
A
R
P
K
Chimpanzee
Pan troglodytes
XP_001166807
625
68782
S140
L
W
K
G
R
P
L
S
V
R
L
A
R
P
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534759
667
72765
S181
L
W
K
G
R
P
L
S
V
R
P
A
R
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNV1
574
63283
S130
L
W
K
G
C
P
L
S
V
R
L
A
R
P
K
Rat
Rattus norvegicus
NP_001011895
615
67858
S131
L
W
K
G
R
P
L
S
V
R
L
A
R
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513281
481
53523
D72
V
T
P
L
W
R
L
D
Y
Q
E
Q
L
K
V
Chicken
Gallus gallus
XP_415080
602
66958
A127
E
P
L
S
K
R
I
A
D
V
V
T
P
L
W
Frog
Xenopus laevis
NP_001093345
612
69426
E146
I
M
Q
K
R
K
Q
E
E
D
G
E
Q
P
E
Zebra Danio
Brachydanio rerio
A4QP75
473
53154
T64
E
R
L
S
D
T
V
T
P
L
W
R
M
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649083
615
68596
P138
V
A
K
A
S
A
D
P
L
Q
K
K
R
A
A
Honey Bee
Apis mellifera
XP_396538
568
64494
S129
K
V
E
E
D
D
Q
S
I
S
I
E
D
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L7S3
809
89004
N232
I
L
D
G
K
T
V
N
S
S
N
L
K
I
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
N.A.
82.3
N.A.
77.5
82
N.A.
34.8
64.1
60.7
32.3
N.A.
36
33.9
N.A.
N.A.
Protein Similarity:
100
99.5
N.A.
85.6
N.A.
82.8
88
N.A.
48.3
76.9
75.6
45.9
N.A.
52.9
50.7
N.A.
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
100
N.A.
6.6
0
13.3
0
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
100
N.A.
20
26.6
40
13.3
N.A.
33.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
9
0
9
0
0
0
42
0
9
17
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
17
9
9
9
9
9
0
0
9
0
0
% D
% Glu:
17
0
9
9
0
0
0
9
9
0
9
17
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
50
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
0
9
0
9
0
9
0
0
9
0
% I
% Lys:
9
0
50
9
17
9
0
0
0
0
9
9
9
17
42
% K
% Leu:
42
9
17
9
0
0
50
0
9
9
34
9
9
9
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% N
% Pro:
0
9
9
0
0
42
0
9
9
0
9
0
9
50
0
% P
% Gln:
0
0
9
0
0
0
17
0
0
17
0
9
9
0
0
% Q
% Arg:
0
9
0
0
42
17
0
0
0
42
0
9
50
0
0
% R
% Ser:
0
0
0
17
9
0
0
50
9
17
0
0
0
0
0
% S
% Thr:
0
9
0
0
0
17
0
9
0
0
0
9
0
9
0
% T
% Val:
17
9
0
0
0
0
17
0
42
9
9
0
0
0
17
% V
% Trp:
0
42
0
0
9
0
0
0
0
0
9
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _