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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRMT2A
All Species:
9.09
Human Site:
S25
Identified Species:
18.18
UniProt:
Q8IZ69
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZ69
NP_073564.3
625
68726
S25
Q
E
S
S
S
A
L
S
C
P
T
V
S
V
P
Chimpanzee
Pan troglodytes
XP_001166807
625
68782
S25
Q
E
S
N
S
A
L
S
C
P
T
V
S
V
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534759
667
72765
T32
P
T
R
R
A
A
G
T
G
P
W
R
A
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNV1
574
63283
L29
V
P
S
S
A
A
P
L
C
Q
K
E
E
A
G
Rat
Rattus norvegicus
NP_001011895
615
67858
S25
Q
D
V
S
A
V
G
S
S
A
A
S
V
C
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513281
481
53523
Chicken
Gallus gallus
XP_415080
602
66958
K25
L
F
T
S
E
I
Y
K
V
E
I
Q
N
L
P
Frog
Xenopus laevis
NP_001093345
612
69426
A35
S
E
M
A
E
V
V
A
E
T
C
H
E
S
K
Zebra Danio
Brachydanio rerio
A4QP75
473
53154
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649083
615
68596
K28
E
I
S
E
N
V
V
K
A
D
E
T
T
L
A
Honey Bee
Apis mellifera
XP_396538
568
64494
E25
E
R
A
D
F
T
S
E
K
Y
K
I
E
V
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L7S3
809
89004
S68
D
E
K
T
N
L
E
S
S
D
T
K
I
T
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
N.A.
82.3
N.A.
77.5
82
N.A.
34.8
64.1
60.7
32.3
N.A.
36
33.9
N.A.
N.A.
Protein Similarity:
100
99.5
N.A.
85.6
N.A.
82.8
88
N.A.
48.3
76.9
75.6
45.9
N.A.
52.9
50.7
N.A.
N.A.
P-Site Identity:
100
93.3
N.A.
13.3
N.A.
26.6
20
N.A.
0
13.3
6.6
0
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
33.3
N.A.
33.3
33.3
N.A.
0
33.3
26.6
0
N.A.
40
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
25
34
0
9
9
9
9
0
9
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
25
0
9
0
0
9
0
% C
% Asp:
9
9
0
9
0
0
0
0
0
17
0
0
0
0
0
% D
% Glu:
17
34
0
9
17
0
9
9
9
9
9
9
25
0
0
% E
% Phe:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
17
0
9
0
0
0
0
9
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% H
% Ile:
0
9
0
0
0
9
0
0
0
0
9
9
9
0
0
% I
% Lys:
0
0
9
0
0
0
0
17
9
0
17
9
0
0
9
% K
% Leu:
9
0
0
0
0
9
17
9
0
0
0
0
0
17
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
17
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
9
9
0
0
0
0
9
0
0
25
0
0
0
0
25
% P
% Gln:
25
0
0
0
0
0
0
0
0
9
0
9
0
0
9
% Q
% Arg:
0
9
9
9
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
9
0
34
34
17
0
9
34
17
0
0
9
17
9
0
% S
% Thr:
0
9
9
9
0
9
0
9
0
9
25
9
9
9
9
% T
% Val:
9
0
9
0
0
25
17
0
9
0
0
17
9
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _