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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRMT2A All Species: 10.3
Human Site: S61 Identified Species: 20.61
UniProt: Q8IZ69 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZ69 NP_073564.3 625 68726 S61 G P Q P G L Y S Y I R D D L F
Chimpanzee Pan troglodytes XP_001166807 625 68782 S61 G P Q P G L Y S Y I R D D L F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534759 667 72765 S102 A P Q P G L Y S Y I R D D L F
Cat Felis silvestris
Mouse Mus musculus Q8BNV1 574 63283 T59 Y I R D D L F T S E I F K L E
Rat Rattus norvegicus NP_001011895 615 67858 D56 G L Y S Y I R D D L F T S E I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513281 481 53523
Chicken Gallus gallus XP_415080 602 66958 K55 G L S P H K I K L L G K Q T F
Frog Xenopus laevis NP_001093345 612 69426 N75 L P K Y I G F N D L K K F L G
Zebra Danio Brachydanio rerio A4QP75 473 53154
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649083 615 68596 I60 R N E F T S E I F K V E V K N
Honey Bee Apis mellifera XP_396538 568 64494 C56 E K L D L Q S C K I K P P K R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L7S3 809 89004 K138 K M S E H E E K E E D E V L F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. 82.3 N.A. 77.5 82 N.A. 34.8 64.1 60.7 32.3 N.A. 36 33.9 N.A. N.A.
Protein Similarity: 100 99.5 N.A. 85.6 N.A. 82.8 88 N.A. 48.3 76.9 75.6 45.9 N.A. 52.9 50.7 N.A. N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 13.3 6.6 N.A. 0 20 13.3 0 N.A. 0 6.6 N.A. N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 33.3 20 N.A. 0 26.6 46.6 0 N.A. 20 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 17 9 0 0 9 17 0 9 25 25 0 0 % D
% Glu: 9 0 9 9 0 9 17 0 9 17 0 17 0 9 9 % E
% Phe: 0 0 0 9 0 0 17 0 9 0 9 9 9 0 42 % F
% Gly: 34 0 0 0 25 9 0 0 0 0 9 0 0 0 9 % G
% His: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 9 9 9 9 0 34 9 0 0 0 9 % I
% Lys: 9 9 9 0 0 9 0 17 9 9 17 17 9 17 0 % K
% Leu: 9 17 9 0 9 34 0 0 9 25 0 0 0 50 0 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 9 % N
% Pro: 0 34 0 34 0 0 0 0 0 0 0 9 9 0 0 % P
% Gln: 0 0 25 0 0 9 0 0 0 0 0 0 9 0 0 % Q
% Arg: 9 0 9 0 0 0 9 0 0 0 25 0 0 0 9 % R
% Ser: 0 0 17 9 0 9 9 25 9 0 0 0 9 0 0 % S
% Thr: 0 0 0 0 9 0 0 9 0 0 0 9 0 9 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 9 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 9 9 9 0 25 0 25 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _