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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRMT2A
All Species:
10
Human Site:
T103
Identified Species:
20
UniProt:
Q8IZ69
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZ69
NP_073564.3
625
68726
T103
F
G
L
Q
P
H
K
T
K
L
F
G
Q
P
P
Chimpanzee
Pan troglodytes
XP_001166807
625
68782
T103
F
G
L
Q
P
H
K
T
K
L
F
G
Q
P
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534759
667
72765
T144
F
G
L
Q
P
H
K
T
K
L
F
G
Q
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNV1
574
63283
P100
I
K
L
F
G
Q
P
P
C
A
F
V
T
F
R
Rat
Rattus norvegicus
NP_001011895
615
67858
F97
Q
S
H
K
I
K
L
F
G
Q
P
P
C
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513281
481
53523
E42
R
N
G
R
E
R
S
E
K
R
Q
S
S
Q
D
Chicken
Gallus gallus
XP_415080
602
66958
P97
L
G
V
R
A
A
K
P
K
A
D
P
M
A
R
Frog
Xenopus laevis
NP_001093345
612
69426
V116
E
R
D
K
A
M
K
V
I
H
G
V
M
W
K
Zebra Danio
Brachydanio rerio
A4QP75
473
53154
S34
N
Q
R
A
I
N
N
S
C
K
P
V
K
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649083
615
68596
Q107
A
F
V
C
F
R
S
Q
E
D
Q
Q
R
A
L
Honey Bee
Apis mellifera
XP_396538
568
64494
A97
W
K
N
Y
K
L
S
A
Q
I
A
K
P
A
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L7S3
809
89004
D184
L
P
N
K
W
Q
S
D
E
L
K
K
F
L
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
N.A.
82.3
N.A.
77.5
82
N.A.
34.8
64.1
60.7
32.3
N.A.
36
33.9
N.A.
N.A.
Protein Similarity:
100
99.5
N.A.
85.6
N.A.
82.8
88
N.A.
48.3
76.9
75.6
45.9
N.A.
52.9
50.7
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
13.3
0
N.A.
6.6
20
6.6
0
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
13.3
6.6
N.A.
13.3
33.3
13.3
20
N.A.
20
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
17
9
0
9
0
17
9
0
0
34
0
% A
% Cys:
0
0
0
9
0
0
0
0
17
0
0
0
9
0
0
% C
% Asp:
0
0
9
0
0
0
0
9
0
9
9
0
0
0
9
% D
% Glu:
9
0
0
0
9
0
0
9
17
0
0
0
0
0
0
% E
% Phe:
25
9
0
9
9
0
0
9
0
0
34
0
9
9
9
% F
% Gly:
0
34
9
0
9
0
0
0
9
0
9
25
0
0
9
% G
% His:
0
0
9
0
0
25
0
0
0
9
0
0
0
0
0
% H
% Ile:
9
0
0
0
17
0
0
0
9
9
0
0
0
0
0
% I
% Lys:
0
17
0
25
9
9
42
0
42
9
9
17
9
0
9
% K
% Leu:
17
0
34
0
0
9
9
0
0
34
0
0
0
9
9
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
17
0
0
% M
% Asn:
9
9
17
0
0
9
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
0
25
0
9
17
0
0
17
17
9
25
34
% P
% Gln:
9
9
0
25
0
17
0
9
9
9
17
9
25
9
0
% Q
% Arg:
9
9
9
17
0
17
0
0
0
9
0
0
9
0
17
% R
% Ser:
0
9
0
0
0
0
34
9
0
0
0
9
9
0
9
% S
% Thr:
0
0
0
0
0
0
0
25
0
0
0
0
9
9
0
% T
% Val:
0
0
17
0
0
0
0
9
0
0
0
25
0
0
0
% V
% Trp:
9
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _