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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRMT2A
All Species:
19.09
Human Site:
Y331
Identified Species:
38.18
UniProt:
Q8IZ69
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZ69
NP_073564.3
625
68726
Y331
H
Q
A
M
A
I
A
Y
F
H
P
Q
K
L
S
Chimpanzee
Pan troglodytes
XP_001166807
625
68782
Y331
R
Q
A
M
A
I
A
Y
F
H
P
Q
K
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534759
667
72765
Y372
G
Q
A
M
A
I
V
Y
F
H
P
Q
K
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNV1
574
63283
Y321
G
Q
A
M
A
I
A
Y
F
H
P
Q
K
L
S
Rat
Rattus norvegicus
NP_001011895
615
67858
H322
G
Q
A
M
A
I
A
H
F
H
P
Q
K
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513281
481
53523
L232
Q
Q
L
N
Q
E
E
L
W
A
Q
K
E
A
V
Chicken
Gallus gallus
XP_415080
602
66958
Y289
G
H
I
M
A
I
V
Y
F
N
P
Q
K
L
S
Frog
Xenopus laevis
NP_001093345
612
69426
Y335
G
Q
V
M
A
I
V
Y
F
N
P
Q
K
L
P
Zebra Danio
Brachydanio rerio
A4QP75
473
53154
T224
Q
S
L
T
P
E
E
T
D
I
H
K
A
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649083
615
68596
A313
T
G
E
L
M
L
V
A
G
I
Y
S
S
N
L
Honey Bee
Apis mellifera
XP_396538
568
64494
G300
D
H
L
M
V
I
V
G
I
H
P
Q
D
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L7S3
809
89004
E422
P
G
V
F
S
N
D
E
D
A
I
T
R
I
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
N.A.
82.3
N.A.
77.5
82
N.A.
34.8
64.1
60.7
32.3
N.A.
36
33.9
N.A.
N.A.
Protein Similarity:
100
99.5
N.A.
85.6
N.A.
82.8
88
N.A.
48.3
76.9
75.6
45.9
N.A.
52.9
50.7
N.A.
N.A.
P-Site Identity:
100
93.3
N.A.
80
N.A.
93.3
86.6
N.A.
6.6
66.6
66.6
0
N.A.
0
40
N.A.
N.A.
P-Site Similarity:
100
93.3
N.A.
80
N.A.
93.3
93.3
N.A.
26.6
73.3
73.3
6.6
N.A.
13.3
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
42
0
59
0
34
9
0
17
0
0
9
17
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
9
0
17
0
0
0
9
0
0
% D
% Glu:
0
0
9
0
0
17
17
9
0
0
0
0
9
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
59
0
0
0
0
0
0
% F
% Gly:
42
17
0
0
0
0
0
9
9
0
0
0
0
0
9
% G
% His:
9
17
0
0
0
0
0
9
0
50
9
0
0
0
0
% H
% Ile:
0
0
9
0
0
67
0
0
9
17
9
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
17
59
0
0
% K
% Leu:
0
0
25
9
0
9
0
9
0
0
0
0
0
67
17
% L
% Met:
0
0
0
67
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
9
0
0
0
17
0
0
0
9
0
% N
% Pro:
9
0
0
0
9
0
0
0
0
0
67
0
0
0
9
% P
% Gln:
17
59
0
0
9
0
0
0
0
0
9
67
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
0
9
0
0
9
0
0
0
0
0
0
9
9
0
42
% S
% Thr:
9
0
0
9
0
0
0
9
0
0
0
9
0
0
9
% T
% Val:
0
0
17
0
9
0
42
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _