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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPUSD2
All Species:
20.3
Human Site:
S446
Identified Species:
40.61
UniProt:
Q8IZ73
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZ73
NP_689473.1
545
61311
S446
L
T
D
S
T
A
P
S
S
E
L
G
K
D
D
Chimpanzee
Pan troglodytes
XP_510311
600
67019
S501
L
T
D
S
T
A
P
S
S
E
L
G
K
D
D
Rhesus Macaque
Macaca mulatta
XP_001096617
682
75894
S583
L
T
D
S
T
A
P
S
S
E
L
G
K
D
S
Dog
Lupus familis
XP_544620
518
57980
S419
L
I
D
S
T
A
P
S
S
E
V
G
K
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q149F1
553
61516
S459
L
I
D
S
T
A
P
S
S
E
L
A
K
D
S
Rat
Rattus norvegicus
NP_001129317
553
61699
S459
L
I
D
S
T
A
P
S
S
E
L
G
K
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426389
480
54854
A405
D
S
E
I
K
E
V
A
T
Y
P
L
N
F
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693475
579
65671
Q462
T
K
C
K
D
G
A
Q
G
R
N
E
Q
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723592
739
82247
C629
S
R
E
T
T
P
P
C
N
E
P
Q
Q
P
E
Honey Bee
Apis mellifera
XP_624656
515
58686
V422
K
L
D
M
E
D
R
V
S
L
S
N
D
K
D
Nematode Worm
Caenorhab. elegans
O16686
432
49992
D367
R
M
E
H
L
A
A
D
T
T
P
I
T
P
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU60
395
44606
G330
I
A
K
R
I
D
A
G
E
R
K
I
V
S
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
75.6
79.4
N.A.
77.9
77.2
N.A.
N.A.
60.3
N.A.
50.9
N.A.
35.4
46.2
30
N.A.
Protein Similarity:
100
90.3
76.8
84.5
N.A.
83.9
83.9
N.A.
N.A.
71.7
N.A.
66.6
N.A.
49.6
60.9
45.6
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
80
86.6
N.A.
N.A.
0
N.A.
0
N.A.
20
20
6.6
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
80
86.6
N.A.
N.A.
33.3
N.A.
6.6
N.A.
53.3
20
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
59
25
9
0
0
0
9
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
9
0
59
0
9
17
0
9
0
0
0
0
9
50
25
% D
% Glu:
0
0
25
0
9
9
0
0
9
59
0
9
0
0
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
0
9
0
9
9
0
0
42
0
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
9
25
0
9
9
0
0
0
0
0
0
17
0
9
0
% I
% Lys:
9
9
9
9
9
0
0
0
0
0
9
0
50
9
0
% K
% Leu:
50
9
0
0
9
0
0
0
0
9
42
9
0
0
0
% L
% Met:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
9
9
9
0
9
% N
% Pro:
0
0
0
0
0
9
59
0
0
0
25
0
0
17
9
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
9
17
0
0
% Q
% Arg:
9
9
0
9
0
0
9
0
0
17
0
0
0
0
0
% R
% Ser:
9
9
0
50
0
0
0
50
59
0
9
0
0
9
25
% S
% Thr:
9
25
0
9
59
0
0
0
17
9
0
0
9
0
9
% T
% Val:
0
0
0
0
0
0
9
9
0
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _