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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALDH16A1 All Species: 11.52
Human Site: S608 Identified Species: 25.33
UniProt: Q8IZ83 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZ83 NP_699160.2 802 85127 S608 R R K S T L A S R L E R Q G A
Chimpanzee Pan troglodytes XP_001172626 802 85017 S608 R R K S T L A S R L E R Q G A
Rhesus Macaque Macaca mulatta XP_001113116 323 33722 D168 L S K N L N Y D T F G L A V P
Dog Lupus familis XP_851694 802 85494 S608 R R E S A L A S R L E R H G V
Cat Felis silvestris
Mouse Mus musculus Q571I9 802 84737 S608 R R K P V L T S Q L E R H G A
Rat Rattus norvegicus Q3T1L0 802 85396 A608 R R K Q V L A A Q L E R H G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519604 638 66871 K483 Y G L F L G G K F Q P P G G R
Chicken Gallus gallus
Frog Xenopus laevis NP_001089655 811 89363 Q611 L R R D E V A Q R L S T L T G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797815 831 90903 Q631 Q R R D E V A Q G I A R L T G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S795 501 54413 L346 K G Q Y E K I L K F I S T A K
Baker's Yeast Sacchar. cerevisiae P40047 520 56602 Q364 E E V F Q G A Q T S D K Q L H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 38.7 84.9 N.A. 81.8 81 N.A. 49.2 N.A. 43.6 N.A. N.A. N.A. N.A. N.A. 41.1
Protein Similarity: 100 99.2 39.4 90.9 N.A. 88 87.9 N.A. 60.8 N.A. 61.1 N.A. N.A. N.A. N.A. N.A. 60.2
P-Site Identity: 100 100 6.6 73.3 N.A. 66.6 66.6 N.A. 6.6 N.A. 26.6 N.A. N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 13.3 80 N.A. 73.3 80 N.A. 6.6 N.A. 40 N.A. N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 21 21.4 N.A.
Protein Similarity: N.A. N.A. N.A. 32.4 35.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 64 10 0 0 10 0 10 10 37 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 19 0 0 0 10 0 0 10 0 0 0 0 % D
% Glu: 10 10 10 0 28 0 0 0 0 0 46 0 0 0 0 % E
% Phe: 0 0 0 19 0 0 0 0 10 19 0 0 0 0 0 % F
% Gly: 0 19 0 0 0 19 10 0 10 0 10 0 10 55 19 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 28 0 10 % H
% Ile: 0 0 0 0 0 0 10 0 0 10 10 0 0 0 0 % I
% Lys: 10 0 46 0 0 10 0 10 10 0 0 10 0 0 10 % K
% Leu: 19 0 10 0 19 46 0 10 0 55 0 10 19 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 0 0 0 0 10 10 0 0 10 % P
% Gln: 10 0 10 10 10 0 0 28 19 10 0 0 28 0 0 % Q
% Arg: 46 64 19 0 0 0 0 0 37 0 0 55 0 0 10 % R
% Ser: 0 10 0 28 0 0 0 37 0 10 10 10 0 0 0 % S
% Thr: 0 0 0 0 19 0 10 0 19 0 0 10 10 19 0 % T
% Val: 0 0 10 0 19 19 0 0 0 0 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _