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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0319L All Species: 17.53
Human Site: S1043 Identified Species: 48.21
UniProt: Q8IZA0 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZA0 NP_079150.3 1049 115658 S1043 Q T P L K A R S P R E E I L _
Chimpanzee Pan troglodytes XP_513307 1049 115667 S1043 Q T P L K A R S P R E E I L _
Rhesus Macaque Macaca mulatta XP_001102000 1015 111828 S1009 Q T P L K A R S P R E E I L _
Dog Lupus familis XP_539600 1052 115974 A1046 Q A P L K A R A P R Q E I L _
Cat Felis silvestris
Mouse Mus musculus Q8K135 1048 115293 S1042 Q T P L K S R S A R E E I L _
Rat Rattus norvegicus NP_001153127 1049 115507 S1043 Q T P L K T R S P R E E I L _
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417781 780 85688
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001335068 1048 115317 K1042 Q G P H K P K K T R E E L L _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648171 1069 117293 L1063 H K Y G T Q K L G R K I K A _
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 95.2 86.7 N.A. 84.3 83.2 N.A. N.A. 64.4 N.A. 50 N.A. 30.7 N.A. N.A. N.A.
Protein Similarity: 100 99.9 96 90.7 N.A. 89.9 89.3 N.A. N.A. 69.9 N.A. 65.6 N.A. 49.2 N.A. N.A. N.A.
P-Site Identity: 100 100 100 78.5 N.A. 85.7 92.8 N.A. N.A. 0 N.A. 50 N.A. 7.1 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 92.8 N.A. 92.8 92.8 N.A. N.A. 0 N.A. 64.2 N.A. 21.4 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 45 0 12 12 0 0 0 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 67 78 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 12 0 12 0 0 0 0 12 0 0 0 0 0 0 % G
% His: 12 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 12 67 0 0 % I
% Lys: 0 12 0 0 78 0 23 12 0 0 12 0 12 0 0 % K
% Leu: 0 0 0 67 0 0 0 12 0 0 0 0 12 78 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 78 0 0 12 0 0 56 0 0 0 0 0 0 % P
% Gln: 78 0 0 0 0 12 0 0 0 0 12 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 67 0 0 89 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 12 0 56 0 0 0 0 0 0 0 % S
% Thr: 0 56 0 0 12 12 0 0 12 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89 % _