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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: H1FOO All Species: 10.91
Human Site: S124 Identified Species: 18.46
UniProt: Q8IZA3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZA3 NP_722575.1 346 35813 S124 K A R G A T G S F K L V P K H
Chimpanzee Pan troglodytes XP_001144407 346 35714 S124 K A R G A T G S F K L V P K H
Rhesus Macaque Macaca mulatta XP_001094128 336 35029 S124 K A R G A T G S F K L V P K H
Dog Lupus familis XP_852262 323 34639 T114 R K V Q P R K T S T M T A P R
Cat Felis silvestris
Mouse Mus musculus Q8VIK3 304 32205 T116 H S K A K G A T G S F K L V P
Rat Rattus norvegicus Q6P747 553 60788 V230 G A S G S F V V V Q K S K T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505393 294 31091 P106 S K T K E A T P K A E S K D T
Chicken Gallus gallus Q5ZM33 559 61833 V231 G A S G S F V V V S N A G K T
Frog Xenopus laevis P15308 273 29292 L85 D P L R L K F L L R T A L N K
Zebra Danio Brachydanio rerio NP_898894 257 26993 A69 R K G V S A Q A I R G Y I K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P02255 256 26341 L68 K E R G G S S L L A I K K Y I
Honey Bee Apis mellifera XP_001121111 224 23571 K36 K S K A Q R E K A S H P P T S
Nematode Worm Caenorhab. elegans P15796 191 19760
Sea Urchin Strong. purpuratus P15869 211 22150 E23 P A H P S S S E M V L A A I T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 89.5 59.2 N.A. 45.9 22.6 N.A. 23.1 22 32.9 31.7 N.A. 29.4 28 25.7 32.3
Protein Similarity: 100 99.1 90.7 69.9 N.A. 54.9 34.7 N.A. 37.2 34.1 45 43 N.A. 43.6 39 38.4 44.2
P-Site Identity: 100 100 100 0 N.A. 0 13.3 N.A. 0 20 0 6.6 N.A. 20 13.3 0 13.3
P-Site Similarity: 100 100 100 20 N.A. 20 26.6 N.A. 0 26.6 6.6 33.3 N.A. 33.3 26.6 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 43 0 15 22 15 8 8 8 15 0 22 15 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 0 8 0 0 8 0 8 8 0 0 8 0 0 0 8 % E
% Phe: 0 0 0 0 0 15 8 0 22 0 8 0 0 0 0 % F
% Gly: 15 0 8 43 8 8 22 0 8 0 8 0 8 0 0 % G
% His: 8 0 8 0 0 0 0 0 0 0 8 0 0 0 22 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 8 0 8 8 8 % I
% Lys: 36 22 15 8 8 8 8 8 8 22 8 15 22 36 8 % K
% Leu: 0 0 8 0 8 0 0 15 15 0 29 0 15 0 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % N
% Pro: 8 8 0 8 8 0 0 8 0 0 0 8 29 8 15 % P
% Gln: 0 0 0 8 8 0 8 0 0 8 0 0 0 0 0 % Q
% Arg: 15 0 29 8 0 15 0 0 0 15 0 0 0 0 8 % R
% Ser: 8 15 15 0 29 15 15 22 8 22 0 15 0 0 8 % S
% Thr: 0 0 8 0 0 22 8 15 0 8 8 8 0 15 22 % T
% Val: 0 0 8 8 0 0 15 15 15 8 0 22 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _