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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: H1FOO All Species: 12.12
Human Site: S161 Identified Species: 20.51
UniProt: Q8IZA3 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZA3 NP_722575.1 346 35813 S161 G K G P K K P S E A K E D P P
Chimpanzee Pan troglodytes XP_001144407 346 35714 S161 G K G P K K P S E A K E D P P
Rhesus Macaque Macaca mulatta XP_001094128 336 35029 S161 G K G P K K P S E A K E D P P
Dog Lupus familis XP_852262 323 34639 D145 K K D P P N P D K V K R G P R
Cat Felis silvestris
Mouse Mus musculus Q8VIK3 304 32205 G146 A A G A K E T G S K K S G L L
Rat Rattus norvegicus Q6P747 553 60788 S275 L C E P K E A S Y S L I R K Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505393 294 31091 A136 S T N D Q S K A A A T K S S E
Chicken Gallus gallus Q5ZM33 559 61833 S278 L C E P K E A S Y S L I K K Y
Frog Xenopus laevis P15308 273 29292 K115 T G A T G R F K L A K P V K T
Zebra Danio Brachydanio rerio NP_898894 257 26993 D99 R A L N K G M D T G V F V R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P02255 256 26341 V98 K K Y L K S A V V N G K L I Q
Honey Bee Apis mellifera XP_001121111 224 23571 K66 S S L Q A I K K Y I A S T Y K
Nematode Worm Caenorhab. elegans P15796 191 19760 K33 T T K E P K A K V A A A H P P
Sea Urchin Strong. purpuratus P15869 211 22150 V53 Y I E K N Y T V D I K K Q A I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 89.5 59.2 N.A. 45.9 22.6 N.A. 23.1 22 32.9 31.7 N.A. 29.4 28 25.7 32.3
Protein Similarity: 100 99.1 90.7 69.9 N.A. 54.9 34.7 N.A. 37.2 34.1 45 43 N.A. 43.6 39 38.4 44.2
P-Site Identity: 100 100 100 33.3 N.A. 20 20 N.A. 6.6 20 13.3 13.3 N.A. 13.3 0 26.6 6.6
P-Site Similarity: 100 100 100 40 N.A. 26.6 33.3 N.A. 26.6 33.3 20 13.3 N.A. 20 0 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 15 8 8 8 0 29 8 8 43 15 8 0 8 0 % A
% Cys: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 0 0 0 15 8 0 0 0 22 0 0 % D
% Glu: 0 0 22 8 0 22 0 0 22 0 0 22 0 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % F
% Gly: 22 8 29 0 8 8 0 8 0 8 8 0 15 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 8 0 0 0 8 0 0 0 15 0 15 0 8 8 % I
% Lys: 15 36 8 8 58 29 15 22 8 8 50 22 8 22 8 % K
% Leu: 15 0 15 8 0 0 0 0 8 0 15 0 8 8 8 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 8 8 8 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 43 15 0 29 0 0 0 0 8 0 36 36 % P
% Gln: 0 0 0 8 8 0 0 0 0 0 0 0 8 0 8 % Q
% Arg: 8 0 0 0 0 8 0 0 0 0 0 8 8 8 8 % R
% Ser: 15 8 0 0 0 15 0 36 8 15 0 15 8 8 0 % S
% Thr: 15 15 0 8 0 0 15 0 8 0 8 0 8 0 8 % T
% Val: 0 0 0 0 0 0 0 15 15 8 8 0 15 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 8 0 0 8 0 0 22 0 0 0 0 8 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _